Recombinant Human DCXR Protein, GST-tagged

• Cat.No.: DCXR-2424H
• Product Overview: Human DCXR full-length ORF ( AAH01470, 1 a.a. - 244 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 52.47 kDa
• AA Sequence: MELFLAGRRVLVTGAGKGIGRGTVQ ALHATGARVVAVSRTQADLDSLVRE CPGIEPVCVDLGDWEATERALGSVG PVDLLVNNAAVALLQPFLEVTKEAF DRSFEVNLRAVIQVSQIVARGLIAR GVPGAIVNVSSQCSQRAVTNHSVYC STKGALDMLTKVMALELGPHKIRVN AVNPTVVMTSMGQATWSDPHKAKTM LNRIPLGKFAEVEHVVNAILFLLSD RSGMTTGSTLPVEGGFWAC
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: DCXR dicarbonyl/L-xylulose reductase [ Homo sapiens ]
• Official Symbol: DCXR
• Synonyms: DCXR; dicarbonyl/L-xylulose reductase; L-xylulose reductase; DCR; KIDCR; SDR20C1; short chain dehydrogenase/reductase family 20C; member 1; carbonyl reductase 2; carbonyl reductase II; sperm surface protein P34H; kidney dicarbonyl reductase; short chain dehydrogenase/reductase family 20C, member 1; XR; HCR2; P34H; HCRII
• Gene ID: 51181
• mRNA Refseq: NM_001195218
• Protein Refseq: NP_001182147
• MIM: 608347
• UniProt ID: Q7Z4W1