DCXR
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Official Full Name
dicarbonyl/L-xylulose reductase
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Overview
The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
DCXR; dicarbonyl/L-xylulose reductase; L-xylulose reductase; DCR; KIDCR; SDR20C1; short chain dehydrogenase/reductase family 20C; member 1; carbonyl reductase 2; carbonyl reductase II; sperm surface protein P34H; kidney dicarbonyl reductase; short chain d;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- SUMO
- Myc
- DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | DCXR-128H | Active Recombinant Human DCXR protein, His-tagged | E.coli | His |
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| Human | DCXR-11874H | Recombinant Human DCXR, GST-tagged | E.coli | GST | 1-244a.a. | |
| Human | DCXR-2424H | Recombinant Human DCXR Protein, GST-tagged | Wheat Germ | GST |
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| Human | DCXR-490H | Recombinant Human DCXR, His tagged | E.coli | His |
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| Human | DCXR-2726H | Recombinant Human Dicarbonyl/L-xylulose Reductase, His-tagged | E.coli | His |
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| Human | DCXR-26175TH | Recombinant Human DCXR, His-tagged | E.coli | His | 244 amino acids |
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| Human | DCXR-7030HCL | Recombinant Human DCXR 293 Cell Lysate | HEK293 | N/A |
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| Human | DCXR-2420HF | Recombinant Full Length Human DCXR Protein, GST-tagged | In Vitro Cell Free System | GST | 244 amino acids |
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| Human | DCXR-3334H | Recombinant Human DCXR protein, His-SUMO-tagged | E.coli | His-SUMO | Met1~Cys244 |
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| Mouse | Dcxr-2488M | Recombinant Mouse Dcxr Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Rat | DCXR-1806R | Recombinant Rat DCXR Protein | Mammalian Cell | His |
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| Rat | DCXR-1464R | Recombinant Rat DCXR Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rat | DCXR-1464R-B | Recombinant Rat DCXR Protein Pre-coupled Magnetic Beads | HEK293 |
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| Zebrafish | DCXR-2390Z | Recombinant Zebrafish DCXR | Mammalian Cell | His |
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| Chicken | DCXR-5798C | Recombinant Chicken DCXR | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
DCXR involved in several pathways and played different roles in them. We selected most pathways DCXR participated on our site, such as Pentose and glucuronate interconversions, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with DCXR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pentose and glucuronate interconversions | CRYL1;XYLB;OXSR1;AKR1B7;UGT2A2;KL;UGT1AB;UGT1A6B;UGP2 |
| Metabolic pathways | UPP2;PAPSS2A;TPH1A;GALNTL4;ACO2;MAOB;IDH3G;ATP6V0E1;NDUFA4L |
DCXR has several biochemical functions, for example, L-xylulose reductase (NADP+) activity, oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor. Some of the functions are cooperated with other proteins, some of the functions could acted by DCXR itself. We selected most functions DCXR had, and list some proteins which have the same functions with DCXR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| L-xylulose reductase (NADP+) activity | |
| oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | AKR1C4;AKR1C6;DCXR;DHRS4;AKR1C3;NDUFS7;CBR1;AKR1C2;AKR1C21 |
DCXR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DCXR here. Most of them are supplied by our site. Hope this information will be useful for your research of DCXR.
DMWD; GSTK1; TRAF6; CRADD; ssrna_ac
- Q&As
- Reviews
Q&As (5)
Ask a questionInhibition of DCXR protein expression is associated with male infertility.
DCXR is a sperm surface protein localized to the sperm acrosome site.
Ureaplasma urealyticum infection can cause epididymal dysfunction leading to decreased expression of the sperm protein DCXR.
DXCR has L-xylulose reductase and bicarbonyl reductase activities that kill bacteria in epididymal fluid.
DCXR can remove certain toxic substances and protect spermatozoa to a certain extent and promote sperm maturation and reduce sperm apoptosis.
Customer Reviews (3)
Write a reviewThe staff were enthusiastic and proactive in communicating with me and solving many technical problems in a timely manner.
The proteins purchased from your company are of very high quality and are suitable for WB experiments.
DCXR proteins purchased are as advertised and the quality of the product is guaranteed.
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