Recombinant Human DDR1 Protein, C-His-tagged
Cat.No. : | DDR1-143H |
Product Overview : | Recombinant Human DDR1 Protein with C-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The discoidin domain receptors (DDRs) are receptor tyrosine kinases with a discoidin homology repeat in their extracellular domains, activated by binding to extracellular matrix collagens. So far, two mammalian DDRs have been identified: DDR1 and DDR2. They are widely expressed in human tissues and may have roles in smooth muscle cell-mediated collagen remodeling. Research studies have implicated aberrant expression and signaling of DDRs in human diseases related to increased matrix degradation and remodeling, such as cardiovascular disease, liver fibrosis, and tumor invasion. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Molecular Mass : | ~44 kDa |
AA Sequence : | DMKGHFDPAKCRYALGMQDRTIPDS DISASSSWSDSTAARHSRLESSDGD GAWCPAGSVFPKEEEYLQVDLQRLH LVALVGTQGRHAGGLGKEFSRSYRL RYSRDGRRWMGWKDRWGQEVISGNE DPEGVVLKDLGPPMVARLVRFYPRA DRVMSVCLRVELYGCLWRDGLLSYT APVGQTMYLSEAVYLNDSTYDGHTV GGLQYGGLGQLADGVVGLDDFRKSQ ELRVWPGYDYVGWSNHSFSSGYVEM EFEFDRLRAFQAMQVHCNNMHTLGA RLPGGVECRFRRGPAMAWEGEPMRH NLGGNLGDPRARAVSVPLGGRVARF LQCRFLFAGPWLLFSEISFISDVVN NSSPALGGTFPPAPWWPPGPPPTNF SSLELEPRGQQPVAKAEGSPTA |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Concentration : | ≥0.5 mg/mL |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | DDR1 discoidin domain receptor tyrosine kinase 1 [ Homo sapiens (human) ] |
Official Symbol : | DDR1 |
Synonyms : | DDR1; discoidin domain receptor tyrosine kinase 1; CAK, discoidin domain receptor family, member 1 , EDDR1, NEP, NTRK4, PTK3A; epithelial discoidin domain-containing receptor 1; CD167; RTK6; tyrosine kinase DDR; cell adhesion kinase; mammary carcinoma kinase 10; tyrosine-protein kinase CAK; protein-tyrosine kinase RTK-6; neuroepithelial tyrosine kinase; PTK3A protein tyrosine kinase 3A; CD167 antigen-like family member A; neurotrophic tyrosine kinase, receptor, type 4; CAK; DDR; NEP; HGK2; PTK3; TRKE; EDDR1; MCK10; NTRK4; PTK3A; |
Gene ID : | 780 |
mRNA Refseq : | NM_001202521 |
Protein Refseq : | NP_001189450 |
MIM : | 600408 |
UniProt ID : | Q08345 |
Products Types
◆ Recombinant Protein | ||
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Ddr1-1151M | Recombinant Mouse Ddr1 Protein(Asp22-Ala415), His-tagged | +Inquiry |
DDR1-7297H | Active Recombinant Human DDR1 protein(Arg444-Val913), His&GST-tagged | +Inquiry |
DDR1-2454H | Recombinant Human DDR1 Protein, GST-tagged | +Inquiry |
DDR1-2453H | Recombinant Human DDR1 Protein | +Inquiry |
◆ Lysates | ||
DDR1-2534HCL | Recombinant Human DDR1 cell lysate | +Inquiry |
DDR1-401MCL | Recombinant Mouse DDR1 cell lysate | +Inquiry |
DDR1-1081RCL | Recombinant Rat DDR1 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1560 | U2OS DDR1 Bioassay Kit | +Inquiry |
Kit-1579 | DDR1 Functional Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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