Recombinant Human DNAJA2, GST-tagged

• Cat.No.: DNAJA2-12055H
• Product Overview: Recombinant Human DNAJA2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: N-term-214a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 [ Homo sapiens ]
• Official Symbol: DNAJA2
• Synonyms: DNAJA2; DnaJ (Hsp40) homolog, subfamily A, member 2; dnaJ homolog subfamily A member 2; CPR3; DNAJ; DNJ3; HIRIP4; HIRA interacting protein 4; HIRA-interacting protein 4; cell cycle progression 3 protein; renal carcinoma antigen NY-REN-14; cell cycle progression restoration gene 3 protein; DJ3; DJA2; RDJ2; PRO3015
• Gene ID: 10294
• mRNA Refseq: NM_005880
• Protein Refseq: NP_005871
• MIM: 611322
• UniProt ID: O60884
• Chromosome Location: 16q12.1
• Pathway: Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem
• Function: ATP binding; glycoprotein binding; heat shock protein binding; metal ion binding; unfolded protein binding

Reviews

11/14/2022

Cheap price, high quality products, worth buying again.

04/01/2022

The product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.

11/26/2021

I have a dedicated staff member who is in contact with me and he keep me informed of the progress of my experiments.

Q&As

What are the biological functions of DNAJA2?

DNAJA2 can act as a synergistic molecular chaperone to help cellular protein translation, folding, degradation, etc.

What are the effects of overexpressing DNAJA2?

Overexpression of DNAJA2 promotes JEV proliferation.

What is the relationship between DNAJA1 and DNAJA2?

They both belong to the DnaJ family of A-type proteins and they can interact with each other.

How is DNAJA2 related to NS3?

DNAJA2 interacts with NS3.

What effect does inhibiting the expression of DNAJA2 have on NS3 and NS5?

Inhibition of DNAJA2 expression promotes ubiquitination modification of NS3 and NS5.