Recombinant Human DNM1 Protein, MYC/DDK-tagged, C13 and N15-labeled
Cat.No. : | DNM1-362H |
Product Overview : | DNM1 MS Standard C13 and N15-labeled recombinant protein (NP_001005336) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 95.9 kDa |
AA Sequence : | MGNRGMEDLIPLVNRLQDAFSAIGQ NADLDLPQIAVVGGQSAGKSSVLEN FVGRDFLPRGSGIVTRRPLVLQLVN ATTEYAEFLHCKGKKFTDFEEVRLE IEAETDRVTGTNKGISPVPINLRVY SPHVLNLTLVDLPGMTKVPVGDQPP DIEFQIRDMLMQFVTKENCLILAVS PANSDLANSDALEVAKEVDPQGQRT IGVITKLDLMDEGTDARDVLENKLL PLRRGYIGVVNRSQKDIDGKKDITA ALAAERKFFLSHPSYRHLADRMGTP YLQKVLNQQLTDHIRDTLPGLRNKL QSQLLSIEKEVEEYKNFRPDDPARK TKALLQMVQQFAVDFEKRIEGSGDQ IDTYELSGGARINRIFHERFPFELV KMEFDEKELRREISYAIKNIHGIRT GLFTPDMAFETIVKKQVKKIREPCL KCVDMVISELISTVRQCTKKLQQYP RLREEMERIVTTHIREREGRTKEQV MLLIDIELAYMNTNHEDFIGFANAQ QRSNQMNKKKTSGNQDEILVIRKGW LTINNIGIMKGGSKEYWFVLTAENL SWYKDDEEKEKKYMLSVDNLKLRDV EKGFMSSKHIFALFNTEQRNVYKDY RQLELACETQEEVDSWKASFLRAGV YPERVGDKEKASETEENGSDSFMHS MDPQLERQVETIRNLVDSYMAIVNK TVRDLMPKTIMHLMINNTKEFIFSE LLANLYSCGDQNTLMEESAEQAQRR DEMLRMYHALKEALSIIGDINTTTV STPMPPPVDDSWLQVQSVPAGRRSP TSSPTPQRRAPAVPPARPGSRGPAP GPPPAGSAMGGAPPVPSRPGASPDP FGPPPQVPSRPNRAPPGVPRITISD PTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | DNM1 dynamin 1 [ Homo sapiens (human) ] |
Official Symbol : | DNM1 |
Synonyms : | DNM1; dynamin 1; DNM; dynamin-1; |
Gene ID : | 1759 |
mRNA Refseq : | NM_001005336 |
Protein Refseq : | NP_001005336 |
MIM : | 602377 |
UniProt ID : | Q05193 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionDNM1 contributes to the formation and maintenance of neural circuits, essential for brain function.
DNM1 plays a key role in endocytosis, facilitating membrane trafficking and cellular transport processes.
DNM1 regulates synaptic plasticity, crucial for learning and memory formation.
Changes in DNM1 function can influence the progression of neurodegenerative diseases, affecting neuronal health and connectivity.
DNM1 is crucial for synaptic vesicle recycling, controlling neurotransmitter release at synapses.
DNM1 impacts cellular signaling in neurons, influencing various neuronal activities and responses.
Mutations in DNM1 are linked to neurological conditions like epilepsy, affecting synaptic function.
Customer Reviews (3)
Write a reviewPrecise protein quantification, ensures data accuracy in our experiments.
Accurate mass spectrometry, essential for precise proteomics analysis.
Efficient peptide synthesis, accelerates our peptide research efficiently.
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