Recombinant Human DNM1L protein(501-570 aa), C-His-tagged
Cat.No. : | DNM1L-2457H |
Product Overview : | Recombinant Human DNM1L protein(O00429)(501-570 aa), fused with C-terminal His tag, was expressed in E. coli. |
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Source : | E. coli |
Species : | Human |
Tag : | C-His |
Protein length : | 501-570 aa |
Form : | 0.15 M Phosphate buffered saline |
AASequence : | FADACGLMNNNIEEQRRNRLARELP SAVSRDKSSKVPSALAPASQEPSPA ASAEADGKLIQDSRRETKNV |
Storage : | Shipped on dry ice. Avoid repeated freeze-thaw cycles. Upon receipt, 2 days when stored at 2 to 8 °C after thawing. Up to 12 months when aliquoted and stored at -20 to -80°C. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | DNM1L dynamin 1-like [ Homo sapiens ] |
Official Symbol : | DNM1L |
Synonyms : | DNM1L; dynamin 1-like; dynamin-1-like protein; DRP1; DVLP; DYMPLE; HDYNIV; VPS1; dynamin-like protein 4; dynamin-like protein IV; Dnm1p/Vps1p-like protein; dynamin-related protein 1; dynamin family member proline-rich carboxyl-terminal domain less; DLP1; EMPF; DYNIV-11; FLJ41912; |
Gene ID : | 10059 |
mRNA Refseq : | NM_005690 |
Protein Refseq : | NP_005681 |
MIM : | 603850 |
UniProt ID : | O00429 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionA mutation in the DNM1L gene may have a genetic predisposition, meaning that the mutation is more likely to occur in a patient's family member.
DNM1L is involved in the regulation of neuronal connections and synaptic function, especially in the endocytosis and release process of synaptic vesicles, thereby affecting the transmission of neural signals.
DNM1L gene mutations can be transmitted in different genetic ways such as autosomal dominant, dominant negative, and dominant homosexual, depending on the type and location of the mutation.
DNM1L gene mutations are associated with a number of neurological-related diseases, including Charcot-Marie-Tooth disease, multiple system atrophy, intellectual disability, and movement disorders.
Mutations in the DNM1L gene may be associated with neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease and Huntington's disease.
Through long-term follow-up and clinical data analysis of patients, the impact of DNM1L gene mutations on disease prognosis, such as age of onset, disease progression and quality of life, can be evaluated.
Customer Reviews (3)
Write a reviewIncrease yield and purity and improve production efficiency in biotechnology production.
Good fluorescence labeling performance in light microscopy technology, which is helpful for cell imaging studies.
In vaccine research, it has been found that it can induce immune protective effect and has potential for disease prevention.
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