Recombinant Mouse Dnm1l Protein, Myc/DDK-tagged
Cat.No. : | Dnm1l-2618M |
Product Overview : | Purified recombinant protein of mouse full-length dynamin 1-like (Dnm1l), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
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Description : | This gene encodes a member of the dynamin family. The encoded protein is localized to the cytoplasm and mitochondrial membrane, is involved in mitochondrial and peroxisomal division, and is essential for mitochondrial fission. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 2. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 78 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Dnm1l dynamin 1-like [ Mus musculus (house mouse) ] |
Official Symbol : | Dnm1l |
Synonyms : | DNM1L; dynamin 1-like; dynamin-1-like protein; dymple; dynamin-like protein 1; dynamin-related protein 1; dynamin family member proline-rich carboxyl-terminal domain less; Drp1; Dnmlp1; python; AI450666; 6330417M19Rik; MGC90593 |
Gene ID : | 74006 |
mRNA Refseq : | NM_001025947 |
Protein Refseq : | NP_001021118 |
UniProt ID : | Q8K1M6 |
Products Types
◆ Recombinant Protein | ||
DNM1L-2457H | Recombinant Human DNM1L protein(501-570 aa), C-His-tagged | +Inquiry |
DNM1L-8494H | Recombinant Human DNM1L Protein, Myc/DDK-tagged | +Inquiry |
DNM1L-777H | Recombinant Human DNM1L Protein, His (Fc)-Avi-tagged | +Inquiry |
DNM1L-2470M | Recombinant Mouse DNM1L Protein, His (Fc)-Avi-tagged | +Inquiry |
DNM1L-8493H | Active Recombinant Human DNM1L Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
DNM1L-6858HCL | Recombinant Human DNM1L 293 Cell Lysate | +Inquiry |
DNM1L-6859HCL | Recombinant Human DNM1L 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionA mutation in the DNM1L gene may have a genetic predisposition, meaning that the mutation is more likely to occur in a patient's family member.
DNM1L is involved in the regulation of neuronal connections and synaptic function, especially in the endocytosis and release process of synaptic vesicles, thereby affecting the transmission of neural signals.
DNM1L gene mutations can be transmitted in different genetic ways such as autosomal dominant, dominant negative, and dominant homosexual, depending on the type and location of the mutation.
DNM1L gene mutations are associated with a number of neurological-related diseases, including Charcot-Marie-Tooth disease, multiple system atrophy, intellectual disability, and movement disorders.
Mutations in the DNM1L gene may be associated with neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease and Huntington's disease.
Through long-term follow-up and clinical data analysis of patients, the impact of DNM1L gene mutations on disease prognosis, such as age of onset, disease progression and quality of life, can be evaluated.
Customer Reviews (3)
Write a reviewIncrease yield and purity and improve production efficiency in biotechnology production.
Good fluorescence labeling performance in light microscopy technology, which is helpful for cell imaging studies.
In vaccine research, it has been found that it can induce immune protective effect and has potential for disease prevention.
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