Recombinant Human DSG1 protein, His&Myc-tagged

• Cat.No.: DSG1-2457H
• Product Overview: Recombinant Human DSG1 protein(Q02413)(50-548aa), fused to N-terminal His tag and C-terminal Myc tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His&Myc
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
  If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 60.4 kDa
• Protein length: 50-548aa
• AA Sequence: EWIKFAAACREGEDNSKRNPIAKIH SDCAANQQVTYRISGVGIDQPPYGI FVINQKTGEINITSIVDREVTPFFI IYCRALNSMGQDLERPLELRVRVLD INDNPPVFSMATFAGQIEENSNANT LVMILNATDADEPNNLNSKIAFKII RQEPSDSPMFIINRNTGEIRTMNNF LDREQYGQYALAVRGSDRDGGADGM SAECECNIKILDVNDNIPYMEQSSY TIEIQENTLNSNLLEIRVIDLDEEF SANWMAVIFFISGNEGNWFEIEMNE RTNVGILKVVKPLDYEAMQSLQLSI GVRNKAEFHHSIMSQYKLKASAISV TVLNVIEGPVFRPGSKTYVVTGNMG SNDKVGDFVATDLDTGRPSTTVRYV MGNNPADLLAVDSRTGKLTLKNKVT KEQYNMLGGKYQGTILSIDDNLQRT CTGTININIQSFGNDDRTNTEPNTK ITTNTGRQESTSSTNYDTSTTSTDS SQVYSSEPGNGAKDLLSDNVHFGP
• Purity: Greater than 90% as determined by SDS-PAGE.
• Storage: Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Gene Information

• Gene Name: DSG1 desmoglein 1 [ Homo sapiens ]
• Official Symbol: DSG1
• Synonyms: DSG1; desmoglein 1; DSG; desmoglein-1; CDHF4; DGI; cadherin family member 4; desmosomal glycoprotein 1; pemphigus foliaceus antigen; DG1; PPKS1; SPPK1
• Gene ID: 1828
• mRNA Refseq: NM_001942
• Protein Refseq: NP_001933
• MIM: 125670
• UniProt ID: Q02413

Reviews

02/22/2023

Its impeccable purity and integrity make it a valuable asset in my research endeavors.

03/02/2022

Their team of experts has been instrumental in resolving any queries or challenges I encountered regarding the application and utilization of the DSG1 protein.

03/22/2021

The DSG1 protein surpasses expectations in terms of quality and is an ideal match for my experimental requirements.

Q&As

How is DSG1 expression regulated in the skin?

Various factors, including cytokines and growth factors, can regulate the expression of DSG1 in skin cells.

Are there any clinical trials focused on DSG1 protein therapies?

Some clinical trials may be exploring DSG1-based therapies for skin disorders, but you should consult clinical trial databases for specific information.

What other medical conditions are associated with DSG1 protein?

DSG1 abnormalities are primarily linked to skin disorders, but some studies suggest potential connections to oral mucosa disorders.

Can DSG1 be used as a biomarker for skin cancer?

While DSG1 is not a direct biomarker for skin cancer, its expression levels may be altered in some skin cancers.

Can DSG1-targeted therapies be used to treat skin conditions?

Research is ongoing, but DSG1-targeted therapies have the potential to treat conditions related to DSG1 deficiencies.