Recombinant Human DYSF Protein, His (Fc)-Avi-tagged

• Cat.No.: DYSF-796H
• Product Overview: Recombinant Human DYSF with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Human
• Tag: His (Fc)-Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: DYSF dysferlin [ Homo sapiens (human) ]
• Official Symbol: DYSF
• Synonyms: MMD1; FER1L1; LGMD2B; LGMDR2
• Gene ID: 8291
• mRNA Refseq: NM_001130987.2
• Protein Refseq: NP_001124459.1
• MIM: 603009
• UniProt ID: O75923

Reviews

08/14/2021

It has good stability and is suitable for long-term storage.

04/09/2021

The detection method is sensitive and can detect trace amounts of protein, which is very suitable for our research.

03/20/2021

DYSF is easy to operate and improves the efficiency of the experiment.

Q&As

Are variants in the DYSF gene associated with insulin resistance?

Yes, some variants in the DYSF gene are associated with insulin resistance, which may be one of the reasons for its increased risk of type 2 diabetes.

What is the role of the DYSF gene in the human body?

The protein encoded by the DYSF gene is a muscle-specific kinase that plays an important role in the structure and function of muscle cells.

How can lifestyle changes reduce the risk of DYSF gene variants?

There is currently no definitive way to alter the variant in the DYSF gene. However, the risk of type 2 diabetes can be reduced by adhering to a healthy lifestyle, such as eating a balanced diet, exercising moderately, avoiding excessive stress, etc.

Is there a specific treatment or intervention for the DYSF gene variant?

There is currently no specific treatment or intervention for the DYSF gene variant. However, the risk of type 2 diabetes can be reduced through a combination of measures such as lifestyle modifications and medications.

Are variants in the DYSF gene related to β cell function?

Yes, some variants in the DYSF gene are also involved in β cell function, which may also be one of the reasons why it affects the risk of type 2 diabetes.

What are the types of DYSF gene variants?

Variants in the DYSF gene include single nucleotide polymorphisms (SNPs), insertions/deletions, and some of these variants are associated with an increased risk of type 2 diabetes.