Recombinant Human DYSF Protein, His-tagged
Cat.No. : | DYSF-684H |
Product Overview : | Recombinant Human DYSF(Met1~Tyr479) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
- Download
Description : | The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Molecular Mass : | 56.9kDa |
Protein length : | Met1~Tyr479 |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | > 95% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Reconstitution : | Reconstitute in PBS or others |
Gene Name : | DYSF dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) [ Homo sapiens ] |
Official Symbol : | DYSF |
Synonyms : | DYSF; dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive); LGMD2B; dysferlin; FER1L1; fer-1-like protein 1; dystrophy-associated fer-1-like 1; dystrophy-associated fer-1-like protein; MMD1; FLJ00175; FLJ90168; |
Gene ID : | 8291 |
mRNA Refseq : | NM_001130455 |
Protein Refseq : | NP_001123927 |
MIM : | 603009 |
UniProt ID : | O75923 |
Products Types
◆ Recombinant Protein | ||
DYSF-796H | Recombinant Human DYSF Protein, His (Fc)-Avi-tagged | +Inquiry |
DYSF-2773H | Recombinant Human DYSF Protein, MYC/DDK-tagged | +Inquiry |
Dysf-2703M | Recombinant Mouse Dysf Protein, Myc/DDK-tagged | +Inquiry |
DYSF-8213Z | Recombinant Zebrafish DYSF | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionYes, some variants in the DYSF gene are associated with insulin resistance, which may be one of the reasons for its increased risk of type 2 diabetes.
The protein encoded by the DYSF gene is a muscle-specific kinase that plays an important role in the structure and function of muscle cells.
There is currently no definitive way to alter the variant in the DYSF gene. However, the risk of type 2 diabetes can be reduced by adhering to a healthy lifestyle, such as eating a balanced diet, exercising moderately, avoiding excessive stress, etc.
There is currently no specific treatment or intervention for the DYSF gene variant. However, the risk of type 2 diabetes can be reduced through a combination of measures such as lifestyle modifications and medications.
Yes, some variants in the DYSF gene are also involved in β cell function, which may also be one of the reasons why it affects the risk of type 2 diabetes.
Variants in the DYSF gene include single nucleotide polymorphisms (SNPs), insertions/deletions, and some of these variants are associated with an increased risk of type 2 diabetes.
Customer Reviews (3)
Write a reviewIt has good stability and is suitable for long-term storage.
The detection method is sensitive and can detect trace amounts of protein, which is very suitable for our research.
DYSF is easy to operate and improves the efficiency of the experiment.
Ask a Question for All DYSF Products
Required fields are marked with *
My Review for All DYSF Products
Required fields are marked with *
Inquiry Basket