Recombinant Human ERMAP Protein (His30-Ala155), C-His tagged

• Cat.No.: ERMAP-2640H
• Product Overview: Recombinant human ERMAP (His30-Ala155) protein fused with the C-terminal His tag was expressed in Mammalian cells.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: C-His
• Molecular Mass: 13.86 kDa
• Protein Length: His30-Ala155
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: ERMAP erythroblast membrane-associated protein (Scianna blood group) [ Homo sapiens (human) ]
• Official Symbol: ERMAP
• Synonyms: ERMAP; erythroblast membrane-associated protein (Scianna blood group); erythroblast membrane associated protein, erythroblast membrane associated protein (RD and SC blood groups), Radin blood group, RD, SC, Scianna blood group; erythroid membrane-associated protein; Radin blood group (Rd); Scianna blood group (Sc); radin blood group antigen; scianna blood group antigen; RD; SC; PRO2801; MGC118810; MGC118811; MGC118812; MGC118813
• Gene ID: 114625
• mRNA Refseq: NM_001017922
• Protein Refseq: NP_001017922
• MIM: 609017
• UniProt ID: Q96PL5

Reviews

11/27/2020

Their prompt and effective responses help ensure smooth and efficient progress, indeed solving any problem that arises.

10/02/2016

The knowledgeable and experienced support team is readily available to address any questions or concerns that researchers may have throughout their experimental journey.

07/02/2016

Its stability and reliability warrant its inclusion in my research protocols, leading to meaningful and conclusive results.

Q&As

Are there any ongoing clinical trials related to ERMAP protein and anemia?

Clinical trials investigating the role of ERMAP protein in anemia and potential therapeutic interventions are currently underway, aiming to advance our understanding and develop new treatment options.

What are the diagnostic implications of ERMAP mutations in anemia?

ERMAP mutations can be identified through genetic testing, which can aid in the diagnosis and classification of anemia, as well as guide treatment strategies.

How does ERMAP protein contribute to the regulation of iron metabolism?

ERMAP protein may play a role in the regulation of iron uptake and utilization by red blood cells, which is critical for the maintenance of normal hemoglobin levels and prevention of iron-deficiency anemia.

How is ERMAP protein involved in the etiology of anemia?

ERMAP protein is essential for the proper development and maturation of red blood cells. Mutations in the ERMAP gene can lead to various types of anemia, such as hereditary spherocytosis.

How does ERMAP protein contribute to the pathophysiology of hemolytic anemia?

ERMAP protein is involved in maintaining the structural integrity of red blood cells, and mutations in the ERMAP gene can lead to hemolytic anemia due to increased fragility and destruction of red blood cells.