Recombinant Human FASLG Protein
| Cat.No. : | FASLG-3855H |
| Product Overview : | Human FASLG full-length ORF (AAH17502.1) recombinant protein without tag. |
- Specification
- Gene Information
- Related Products
| Description : | This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014] |
| Source : | Wheat Germ |
| Species : | Human |
| Form : | Liquid |
| Molecular Mass : | 31.5 kDa |
| AA Sequence : | MQQPFNYPYPQIYWVDSSASSPWAP PGTVLPCPTSVPRRPGQRRPPPPPP PPPLPPPPPPPPLPPLPLPPLKKRG NHSTGLCLLVMFFMVLVALVGLGLG MFQLFHLQKELAELRESTSQMHTAS SLEKQIGHPSPPPEKKELRKVAHLT GKSNSRSMPLEWEDTYGIVLLSGVK YKKGGLVINETGLYFVYSKVYFRGQ SCNNLPLSHKVYMRNSKYPQDLVMM EGKMMSYCTTGQMWARSSYLGAVFN LTSADHLYVNVSELSLVNFEESQTF FGLYKL |
| Applications : | Antibody Production Functional Study Compound Screening |
| Usage : | Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
| Notes : | Best use within three months from the date of receipt of this protein. |
| Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : | 25 mM Tris-HCl of pH 8.0 containing 2% glycerol. |
| Gene Name : | FASLG Fas ligand (TNF superfamily, member 6) [ Homo sapiens ] |
| Official Symbol : | FASLG |
| Synonyms : | FASLG; Fas ligand (TNF superfamily, member 6); APT1LG1, TNFSF6, tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6; CD178; FasL; APTL; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; FASL; CD95L; CD95-L; TNFSF6; APT1LG1; |
| Gene ID : | 356 |
| mRNA Refseq : | NM_000639 |
| Protein Refseq : | NP_000630 |
| MIM : | 134638 |
| UniProt ID : | P48023 |
Products Types
| ◆ Lysates | ||
| FASLG-6324HCL | Recombinant Human FASLG 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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