Recombinant Human FGD2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FGD2-2709H
• Product Overview: FGD2 MS Standard C13 and N15-labeled recombinant protein (NP_775829) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene belongs to a family of guanine nucleotide exchange factors (GEFs) which control cytoskeleton-dependent membrane rearrangements by activating the cell division cycle 42 (CDC42) protein. This gene is expressed in B lymphocytes, macrophages, and dendritic cells. The encoded protein may play a role in leukocyte signaling and vesicle trafficking in antigen-presenting cells in the immune system.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 74.9 kDa
• AA Sequence: MKGASEEKLASVSNLVTVFENSRTP EAAPRGHRLEDVHHRPECRPPESPG PREKTNVGEAVGSEPRTVSRRYLNS LKNKLSSEAWRKSCQPVTLSGSGTQ EPEKKIVQELLETEQAYVARLHLLD QVFFQELLKTARSSKAFPEDVVRVI FSNISSIYQFHSQFFLPELQRRLDD WTANPRIGDVIQKLAPFLKMYSEYV KNFERAAELLATWTDKSPLFQEVLT RIQSSEASGSLTLQHHMLEPVQRIP RYELLLKEYIQKLPAQAPDQADAQK ALDMIFSAAQHSNAAITEMERLQDL WEVYQRLGLEDDIVDPSNTLLREGP VLKISFRRNDPMERYLFLFNNMLLY CVPRVIQVGAQFQVRTRIDVAGMKV RELMDAEFPHSFLVSGKQRTLELQA RSQEEMISWMQAFQAAIDQIEKRNE TFKAAAQGPEGDIQEQELQSEELGL RAPQWVRDKMVTMCMRCQEPFNALT RRRHHCRACGYVVCARCSDYRAELK YDDNRPNRVCLHCYAFLTGNVLPEA KEDKRRGILEKGSSATPDQSLMCSF LQLIGDKWGKSGPRGWCVIPRDDPL VLYVYAAPQDMRAHTSIPLLGYQVT VGPQGDPRVFQLQQSGQLYTFKAET EELKGRWVKAMERAASGWSPSWPND GDLSDTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FGD2 FYVE, RhoGEF and PH domain containing 2 [ Homo sapiens (human) ]
• Official Symbol: FGD2
• Synonyms: FGD2; FYVE, RhoGEF and PH domain containing 2; ZFYVE4; FYVE, RhoGEF and PH domain-containing protein 2; FGD1 family, member 2; FLJ00276 protein; epididymis secretory sperm binding protein; zinc finger FYVE domain-containing protein 4
• Gene ID: 221472
• mRNA Refseq: NM_173558
• Protein Refseq: NP_775829
• MIM: 605091
• UniProt ID: Q7Z6J4