Recombinant Human FLT3 Protein, GMP Grade, Animal-Free
Cat.No. : | FLT3-29HG |
Product Overview : | GMP Recombinant Human FLT3 protein with out tag was expressed in E. coli and manufactured using animal-derived component free materials. |
- Specification
- Gene Information
- Related Products
Description : | Flt3-Ligand is a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand binds to cells expressing the tyrosine kinase receptor Flt3. Flt3-Ligand, by itself does not stimulate proliferation of early hematopoietic cells, but synergizes with other CSFs and interleukins to induce growth and differentiation. Unlike SCF, Flt3-Ligand exerts no activity on mast cells. Multiple isoforms of Flt3-Ligand have been identified. The predominant biologically active form is anchored to the cell surface as the extracellular domain of a transmembrane protein (209 a.a.). The membrane-bound isoform can be proteolytically cleaved to generate a biologically active soluble isoform. |
Source : | E. coli |
Species : | Human |
AA Sequence : | MTQDCSFQHSPISSDFAVKIRELSD YLLQDYPVTVASNLQDEELCGGLWR LVLAQRWMERLKTVAGSKMQGLLER VNTEIHFVTKCAFQPPPSCLRFVQT NISRLLQETSEQLVALKPWITRQNF SRCLELQCQPDSSTLPPPWSPRPLE ATAPTA |
Purity : | ≥ 98% by SDS-PAGE gel and HPLC analyses. |
Gene Name : | FLT3 fms-related tyrosine kinase 3 [ Homo sapiens (human) ] |
Official Symbol : | FLT3 |
Synonyms : | FLT3; fms-related tyrosine kinase 3; receptor-type tyrosine-protein kinase FLT3; CD135; FLK2; STK1; STK-1; CD135 antigen; FL cytokine receptor; fetal liver kinase 2; fms-like tyrosine kinase 3; stem cell tyrosine kinase 1; growth factor receptor tyrosine kinase type III; FLK-2; |
Gene ID : | 2322 |
mRNA Refseq : | NM_004119 |
Protein Refseq : | NP_004110 |
MIM : | 136351 |
UniProt ID : | P36888 |
Products Types
◆ Recombinant Protein | ||
FLT3-4370H | Active Recombinant Human FLT3 Protein, GST-tagged | +Inquiry |
Flt3-10555M | Recombinant Mouse Flt3 Protein, His (Fc)-Avi-tagged | +Inquiry |
FLT3-4371H | Recombinant Human FLT3 Protein, GST-tagged | +Inquiry |
Flt3-3045M | Recombinant Mouse Flt3 Protein, Myc/DDK-tagged | +Inquiry |
FLT3-98P | Active Recombinant Porcine FLT-3 Ligand Protein | +Inquiry |
◆ Lysates | ||
FLT3-970MCL | Recombinant Mouse FLT3 cell lysate | +Inquiry |
FLT3-2561HCL | Recombinant Human FLT3 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1593 | Flt3 Activity Assay Kit | +Inquiry |
Kit-1592 | Flt3 ActivityAssay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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