Recombinant Human FUT8 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FUT8-5111H
• Product Overview: FUT8 MS Standard C13 and N15-labeled recombinant protein (NP_835367) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 66.3 kDa
• AA Sequence: MRPWTGSWRWIMLILFAWGTLLFYI GGHLVRDNDHPDHSSRELSKILAKL ERLKQQNEDLRRMAESLRIPEGPID QGPAIGRVRVLEEQLVKAKEQIENY KKQTRNGLGKDHEILRRRIENGAKE LWFFLQSELKKLKNLEGNELQRHAD EFLLDLGHHERSIMTDLYYLSQTDG AGDWREKEAKDLTELVQRRITYLQN PKDCSKAKKLVCNINKGCGYGCQLH HVVYCFMIAYGTQRTLILESQNWRY ATGGWETVFRPVSETCTDRSGISTG HWSGEVKDKNVQVVELPIVDSLHPR PPYLPLAVPEDLADRLVRVHGDPAV WWVSQFVKYLIRPQPWLEKEIEEAT KKLGFKHPVIGVHVRRTDKVGTEAA FHPIEEYMVHVEEHFQLLARRMQVD KKRVYLATDDPSLLKEAKTKYPNYE FISDNSISWSAGLHNRYTENSLRGV ILDIHFLSQADFLVCTFSSQVCRVA YEIMQTLHPDASANFHSLDDIYYFG GQNAHNQIAIYAHQPRTADEIPMEP GDIIGVAGNHWDGYSKGVNRKLGRT GLYPSYKVREKIETVKYPTYPEAEK SGPTRTRRLEQKLISEEDLAANDIL DYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FUT8 fucosyltransferase 8 [ Homo sapiens (human) ]
• Official Symbol: FUT8
• Synonyms: FUT8; fucosyltransferase 8 (alpha (1,6) fucosyltransferase); alpha-(1,6)-fucosyltransferase; alpha1-6FucT; glycoprotein 6-alpha-L-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; MGC26465
• Gene ID: 2530
• mRNA Refseq: NM_178154
• Protein Refseq: NP_835367
• MIM: 602589
• UniProt ID: Q9BYC5