Recombinant Human GAD2 Protein, GST-tagged
Cat.No. : | GAD2-4655H |
Product Overview : | Human GAD2 full-length ORF ( NP_000809.1, 1 a.a. - 585 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 91.8 kDa |
AA Sequence : | MASPGSGFWSFGSEDGSGDSENPGT ARAWCQVAQKFTGGIGNKLCALLYG DAEKPAESGGSQPPRAAARKAACAC DQKPCSCSKVDVNYAFLHATDLLPA CDGERPTLAFLQDVMNILLQYVVKS FDRSTKVIDFHYPNELLQEYNWELA DQPQNLEEILMHCQTTLKYAIKTGH PRYFNQLSTGLDMVGLAADWLTSTA NTNMFTYEIAPVFVLLEYVTLKKMR EIIGWPGGSGDGIFSPGGAISNMYA MMIARFKMFPEVKEKGMAALPRLIA FTSEHSHFSLKKGAAALGIGTDSVI LIKCDERGKMIPSDLERRILEAKQK GFVPFLVSATAGTTVYGAFDPLLAV ADICKKYKIWMHVDAAWGGGLLMSR KHKWKLSGVERANSVTWNPHKMMGV PLQCSALLVREEGLMQNCNQMHASY LFQQDKHYDLSYDTGDKALQCGRHV DVFKLWLMWRAKGTTGFEAHVDKCL ELAEYLYNIIKNREGYEMVFDGKPQ HTNVCFWYIPPSLRTLEDNEERMSR LSKVAPVIKARMMEYGTTMVSYQPL GDKVNFFRMVISNPAATHQDIDFLI EEIERLGQDL |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) [ Homo sapiens ] |
Official Symbol : | GAD2 |
Synonyms : | GAD2; glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); glutamate decarboxylase 2 (pancreatic islets and brain, 65kD); glutamate decarboxylase 2; GAD65; GAD-65; 65 kDa glutamic acid decarboxylase; Glutamate decarboxylase-2 (pancreas); glutamate decarboxylase 65 kDa isoform; MGC161605; MGC161607; |
Gene ID : | 2572 |
mRNA Refseq : | NM_000818 |
Protein Refseq : | NP_000809 |
MIM : | 138275 |
UniProt ID : | Q05329 |
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◆ Lysates | ||
GAD2-001MCL | Recombinant Mouse GAD2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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