Recombinant Human HERC3 Protein, GST-tagged

• Cat.No.: HERC3-4691H
• Product Overview: Human HERC3 partial ORF ( NP_055421, 1 a.a. - 109 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: HERC3 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 37.73 kDa
• AA Sequence: MLCWGYWSLGQPGISTNLQGIVAEP QVCGFISDRSVKEVACGGNHSVFLL EDGEVYTCGLNTKGQLGHEREGNKP EQIGALADQHIIHVACGESHSLALS DRGQLFSWG
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 [ Homo sapiens ]
• Official Symbol: HERC3
• Synonyms: HERC3; HECT and RLD domain containing E3 ubiquitin protein ligase 3; hect domain and RLD 3; probable E3 ubiquitin-protein ligase HERC3; KIAA0032; HECT domain and RCC1-like domain-containing protein 3
• Gene ID: 8916
• mRNA Refseq: NM_014606
• Protein Refseq: NP_055421
• MIM: 605200
• UniProt ID: Q15034