Recombinant Human HERC4, GST-tagged
Cat.No. : | HERC4-178H |
Product Overview : | Recombinant human HERC4 (642-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | HERC4 or HECT and RLD domain containing E3 ubiquitin protein ligase 4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD domain is predicted to act as a guanine nucleotide exchange factor for small G proteins. HERC4 is highly expressed in adult and fetal brain and in all specific brain regions examined. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~71 kDa |
Purity : | >80% by densitometry |
Applications : | Western Blot |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 [ Homo sapiens ] |
Official Symbol : | HERC4 |
Synonyms : | HERC4; HECT and RLD domain containing E3 ubiquitin protein ligase 4; hect domain and RLD 4; probable E3 ubiquitin-protein ligase HERC4; DKFZP564G092; KIAA1593; HECT domain and RCC1-like domain-containing protein 4; DKFZp564G092; |
Gene ID : | 26091 |
mRNA Refseq : | NM_015601 |
Protein Refseq : | NP_056416 |
MIM : | 609248 |
UniProt ID : | Q5GLZ8 |
Chromosome Location : | 10 |
Pathway : | Ubiquitin mediated proteolysis, organism-specific biosystem; Ubiquitin mediated proteolysis, conserved biosystem; |
Function : | acid-amino acid ligase activity; ligase activity; ubiquitin-protein ligase activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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