Recombinant Human HEXA Protein (His318-Thr529), His tagged

• Cat.No.: HEXA-2445H
• Product Overview: Recombinant human HEXA (His318-Thr529) protein fused with His tag was expressed in E. coli.

Specification

• Description: Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized
• Molecular Mass: 26.95 kDa
• Protein Length: His318-Thr529
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Lyophilized from a solution in PBS pH 7.4, 0.02 % NLS, 1mM EDTA, 4 % Trehalose, 1 % Mannitol.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: HEXA hexosaminidase A (alpha polypeptide) [ Homo sapiens (human) ]
• Official Symbol: HEXA
• Synonyms: HEXA; hexosaminidase A (alpha polypeptide); beta-hexosaminidase subunit alpha; GM2 gangliosidosis; Tay Sachs disease; hexosaminidase subunit A; beta-N-acetylhexosaminidase subunit alpha; N-acetyl-beta-glucosaminidase subunit alpha; TSD; MGC99608
• Gene ID: 3073
• mRNA Refseq: NM_000520
• Protein Refseq: NP_000511
• MIM: 606869
• UniProt ID: P06865