Recombinant Human High-mobility Group Box 1, His-tagged
Cat.No. : | HMGB1-532H |
Product Overview : | Recombinant human HMGB1 was expressed inHigh Five insect cellsand purified by conventional chromatography techniques. MW = 25kDa (223aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | HMGB1-532H |
Description : | High mobility group box1 protein (HMGB1) is a very abundant chromatin-binding protein residing in the eukaryotic cell nucleus and acting in the assembly of nucleoprotein complexes. Inside the cell, HMGB1 binds to DNA and has a role in transcriptional regulation. Outside the cell, HMGB1 acts as a cytokine and has activities that resemble those of tumor necrosis factor. |
Source : | High Fiveinsect cells. |
Amino Acid Sequence : | MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK DPNAPKRPPS AFFLFCSEYR PKIKGEHPGL SIGDVAKKLG EMWNNTAADD KQPYEKKAAK LKEKYEKDIA AYRAKGKPDA AKKGVVKAEK SKKKKEEEED EEDEEDEEEE EDEEDEDEEE DDDDELEHHH HHH. |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 0.5 mM DTT, 1 mM EDTA, 10% glycerol. |
Purity : | > 95% by SDS – PAGE. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Endotoxin Level : | < 1.0 EU per 1 μg of protein (determined by LAL method). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | HMGB1 high-mobility group box 1 [ Homo sapiens ] |
Synonyms : | HMGB1; DKFZp686A04236; HMG1; HMG3; SBP-1; HMG3; high-mobility group box 1; Amphoterin; OTTHUMP00000018199; OTTHUMP00000190860; high mobility group protein 1; Sulfoglucuronyl carbohydrate binding protein; high-mobility group (nonhistone chromosomal) protein 1; Amphoterin, High-Mobility Group Box 1 |
Gene ID : | 3146 |
mRNA Refseq : | NM_002128 |
Protein Refseq : | NP_002119 |
MIM : | 601912 |
UniProt ID : | P09429 |
Chromosome Location : | 13q12 |
Function : | DNA bending activity; DNA binding; transcription factor binding |
Products Types
◆ Native Protein | ||
HMGB1-8447B | Active Native Bovine HMGB1 | +Inquiry |
◆ Lysates | ||
HMGB1-1677MCL | Recombinant Mouse HMGB1 cell lysate | +Inquiry |
HMGB1-2076HCL | Recombinant Human HMGB1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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