Recombinant Human HSD11B2 Protein

• Cat.No.: HSD11B2-2361H
• Product Overview: Recombinant human HSD11B2 protein without tag was expressed in E. coli.

Specification

• Description: Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.
• Source: E. coli
• Species: Human
• Tag: Tag Free
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 [ Homo sapiens (human) ]
• Official Symbol: HSD11B2
• Synonyms: HSD11B2; hydroxysteroid (11-beta) dehydrogenase 2; corticosteroid 11-beta-dehydrogenase isozyme 2; SDR9C3; short chain dehydrogenase/reductase family 9C; member 3; 11-DH2; 11-beta-HSD2; -HSD11 type II; 11-beta-hydroxysteroid dehydrogenase type 2; 11-beta-hydroxysteroid dehydrogenase type II; NAD-dependent 11-beta-hydroxysteroid dehydrogenase; short chain dehydrogenase/reductase family 9C member 3; AME; AME1; HSD2; HSD11K
• Gene ID: 3291
• mRNA Refseq: NM_000196
• Protein Refseq: NP_000187
• MIM: 614232
• UniProt ID: P80365