Recombinant Human HSF1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | HSF1-3964H |
Product Overview : | HSF1 MS Standard C13 and N15-labeled recombinant protein (NP_005517) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | The product of this gene is a transcription factor that is rapidly induced after temperature stress and binds heat shock promoter elements (HSE). This protein plays a role in the regulation of lifespan. Expression of this gene is repressed by phosphorylation, which promotes binding by heat shock protein 90. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 57.1 kDa |
AA Sequence : | MDLPVGPGAAGPSNVPAFLTKLWTL VSDPDTDALICWSPSGNSFHVFDQG QFAKEVLPKYFKHNNMASFVRQLNM YGFRKVVHIEQGGLVKPERDDTEFQ HPCFLRGQEQLLENIKRKVTSVSTL KSEDIKIRQDSVTKLLTDVQLMKGK QECMDSKLLAMKHENEALWREVASL RQKHAQQQKVVNKLIQFLISLVQSN RILGVKRKIPLMLNDSGSAHSMPKY SRQFSLEHVHGSGPYSAPSPAYSSS SLYAPDAVASSGPIISDITELAPAS PMASPGGSIDERPLSSSPLVRVKEE PPSPPQSPRVEEASPGRPSSVDTLL SPTALIDSILRESEPAPASVTALTD ARGHTDTEGRPPSPPPTSTPEKCLS VACLDKNELSDHLDAMDSNLDNLQT MLSSHGFSVDTSALLDLFSPSVTVP DMSLPDLDSSLASIQELLSPQEPPR PPEAENSSPDSGKQLVHYTAQPLFL LDPGSVDTGSNDLPVLFELGEGSYF SEGDGFAEDPTISLLTGSEPPKAKD PTVSTRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | HSF1 heat shock transcription factor 1 [ Homo sapiens (human) ] |
Official Symbol : | HSF1 |
Synonyms : | HSF1; heat shock transcription factor 1; heat shock factor protein 1; HSTF1; HSF 1; HSTF 1; |
Gene ID : | 3297 |
mRNA Refseq : | NM_005526 |
Protein Refseq : | NP_005517 |
MIM : | 140580 |
UniProt ID : | Q00613 |
Products Types
◆ Recombinant Protein | ||
HSF1-2127H | Recombinant Human HSF1 Protein, MYC/DDK-tagged | +Inquiry |
HSF1-5085H | Recombinant Human HSF1 Protein, GST-tagged | +Inquiry |
Hsf1-1183M | Recombinant Mouse Hsf1 Protein, MYC/DDK-tagged | +Inquiry |
HSF1-9140Z | Recombinant Zebrafish HSF1 | +Inquiry |
HSF1-3369H | Recombinant Human HSF1 Protein (Val15-Pro288), His tagged | +Inquiry |
◆ Lysates | ||
HSF1-339HCL | Recombinant Human HSF1 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionHSF1 is predominantly localized in the cytoplasm of cells, and it undergoes nuclear translocation upon activation.
The role of HSF1 includes regulating protein homeostasis and the heat shock response, ensuring cellular proteostasis.
Dysregulation or abnormal expression of HSF1 is associated with conditions such as cancer, neurodegenerative disorders, and metabolic diseases.
HSF1 influences cellular processes such as apoptosis and senescence, playing a role in cell fate decisions under stress conditions.
Heat shock factor 1 (HSF1) primarily functions in cellular stress responses, orchestrating the heat shock response.
There are potential therapeutic implications related to HSF1 in diseases involving cellular stress, making it a target for drug development.
HSF1 becomes activated in response to cellular stress, such as heat shock, and it induces the expression of heat shock proteins.
Customer Reviews (3)
Write a reviewThe manufacturer's commitment to open science principles resonated with our lab's dedication to transparent research.
We valued the educational webinars and documentation that enhanced our team's proficiency in utilizing the product.
Its association with impactful research publications contributed to its reputation as a valuable scientific tool.
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