Description : |
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. |
Source : |
E. coli |
Species : |
Human |
Form : |
Solution |
Molecular Mass : |
63 kDa |
Protein Length : |
573 |
AA Sequence : |
MLRLPTVFRQMRPVSRVLAPHLTRA YAKDVKFGADARALMLQGVDLLADA VAVTMGPKGRTVIIEQSWGSPKVTK DGVTVAKSIDLKDKYKNIGAKLVQD VANNTNEEAGDGTTTATVLARSIAK EGFEKISKGANPVEIRRGVMLAVDA VIAELKKQSKPVTTPEEIAQVATIS ANGDKEIGNIISDAMKKVGRKGVIT VKDGKTLNDELEIIEGMKFDRGYIS PYFINTSKGQKCEFQDAYVLLSEKK ISSIQSIVPALEIANAHRKPLVIIA EDVDGEALSTLVLNRLKVGLQVVAV KAPGFGDNRKNQLKDMAIATGGAVF GEEGLTLNLEDVQPHDLGKVGEVIV TKDDAMLLKGKGDKAQIEKRIQEII EQLDVTTSEYEKEKLNERLAKLSDG VAVLKVGGTSDVEVNEKKDRVTDAL NATRAAVEEGIVLGGGCALLRCIPA LDSLTPANEDQKIGIEIIKRTLKIP AMTIAKNAGVEGSLIVEKIMQSSSE VGYDAMAGDFVNMVEKGIIDPTKVV RTALLDAAGVASLLTTAEVVVTEIP KEEKDPGMGAMGGMGGGMGGGMF |
Purity : |
> 95% |
Applications : |
WB |
Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : |
4°C |
Concentration : |
1 mg/mL |
Storage Buffer : |
Tris-HCl (pH 7.5). Sterile-filtered colorless solution. |
Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |