Recombinant Human IA2 Protein, GST-tagged
Cat.No. : | PTPRN-02H |
Product Overview : | Recombinant human PTPRN protein with a GST-tag was expressed in E. coli |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Molecular Mass : | The protein has a calculated MW of 68.6 kDa. |
AA Sequence : | MSPILGYWKIKGLVQPTRLLLEYLE EKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYI ADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSK LPEMLKMFEDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPK LVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKSDLVPRG SRQQDKERLAALGPEGAHGDTTFEY QDLCRQHMATKSLFNRAEGPPEPSR VSSVSSQFSDAAQASPSSHSSTPSW CEEPAQANMDISTGHMILAYMEDHL RNRDRLAKEWQALCAYQAEPNTCAT AQGEGNIKKNRHPDFLPYDHARIKL KVESSPSRSDYINASPIIEHDPRMP AYIATQGPLSHTIADFWQMVWESGC TVIVMLTPLVEDGVKQCDRYWPDEG ASLYHVYEVNLVSEHIWCEDFLVRS FYLKNVQTQETRTLTQFHFLSWPAE GTPASTRPLLDFRRKVNKCYRGRSC PIIVHCSDGAGRTGTYILIDMVLNR MAKGVKEIDIAATLEHVRDQRPGLV RSKDQFEFALTAVAEEVNAILKALP Q |
Purity : | >95% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Storage Buffer : | Lyophilized from 50mM Tris -HCI, 300mM NaCl, pH8.0 |
Gene Name : | PTPRN protein tyrosine phosphatase receptor type N [ Homo sapiens (human) ] |
Official Symbol : | PTPRN |
Synonyms : | PTPRN; protein tyrosine phosphatase receptor type N; IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP; receptor-type tyrosine-protein phosphatase-like N; ICA 512; PTP IA-2; insulinoma-associated tyrosine-phosphatase-like protein; islet cell antigen 2; islet cell antigen 512; islet cell autoantigen 3; protein tyrosine phosphatase-like N; EC 3.1.3.48 |
Gene ID : | 5798 |
mRNA Refseq : | NM_002846 |
Protein Refseq : | NP_002837 |
MIM : | 601773 |
UniProt ID : | Q16849 |
Products Types
◆ Recombinant Protein | ||
PTPRN-674H | Recombinant Human PTPRN Protein, DDK-tagged | +Inquiry |
PTPRN-01H | Recombinant Human PTPRN | +Inquiry |
PTPRN-4500R | Recombinant Rat PTPRN Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPRN-0047H | Recombinant Human PTPRN Protein | +Inquiry |
PTPRN-8H | Recombinant Human PTPRN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PTPRN-1440HCL | Recombinant Human PTPRN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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