Recombinant Human PTPRN
Cat.No. : | PTPRN-01H |
Product Overview : | Recombinant Human PTPRN protein, a DNA sequence encoding the amino acid (605-979) was expressed in E. coli and purified by Affinity chromatography, RT-HPLC. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants. |
Source : | E. coli |
Species : | Human |
Form : | 1×PBS |
Molecular Mass : | 42.3kDa |
AA Sequence : | RQQDKERLAALGPEGAHGDTTFEYQ DLCRQHMATKSLFNRAEGPPEPSRV SSVSSQFSDAAQASPSSHSSTPSW CEEPAQANMDISTGHMILAYMEDHL RNRDRLAKEWQALCAYQAEPNTCAT AQGEGNIKKNRHPDFLPYDHARIK LKVESSPSRSDYINASPIIEHDPRM PAYIATQGPLSHTIADFWQMVWESG CTVIVMLTPLVEDGVKQCDRYWPD EGASLYHVYEVNLVSEHIWCEDFLV RSFYLKNVQTQETRTLTQFHFLSWP AEGTPASTRPLLDFRRKVNKCYRG RSCPIIVHCSDGAGRTGTYILIDMV LNRMAKGVKEIDIAATLEHVRDQRP GLVRSKDQFEFALTAVAEEVNAILK ALPQ |
Endotoxin : | <1.0eu g purified protein (lal>1.0eu> |
Purity : | >99% as determined by RT-HPLC |
Storage : | Can be stored at +4℃ short term (1-2 weeks). For long term storage, store at -20℃ or -70℃ |
Gene Name : | PTPRN protein tyrosine phosphatase, receptor type, N [ Homo sapiens ] |
Official Symbol : | PTPRN |
Synonyms : | PTPRN; protein tyrosine phosphatase, receptor type, N; receptor-type tyrosine-protein phosphatase-like N; IA 2; ICA 512; PTP IA-2; islet cell antigen 2; islet cell antigen 512; islet cell autoantigen 3; protein tyrosine phosphatase-like N; IA2; IA-2; ICA512; R-PTP-N; IA-2/PTP; FLJ16131; |
Gene ID : | 5798 |
mRNA Refseq : | NM_001199763 |
Protein Refseq : | NP_001186692 |
MIM : | 601773 |
UniProt ID : | Q16849 |
Chromosome Location : | 2q35-q36.1 |
Pathway : | Type I diabetes mellitus, organism-specific biosystem; Type I diabetes mellitus, conserved biosystem; |
Function : | GTPase binding; hydrolase activity; phosphatase activity; protein binding; protein tyrosine phosphatase activity; receptor activity; transmembrane receptor protein tyrosine phosphatase activity; |
Products Types
◆ Recombinant Protein | ||
PTPRN-8H | Recombinant Human PTPRN Protein, His (Fc)-Avi-tagged | +Inquiry |
PTPRN-256H | Recombinant Human PTPRN Protein, Flag-tagged | +Inquiry |
PTPRN-02H | Recombinant Human IA2 Protein, GST-tagged | +Inquiry |
PTPRN-674H | Recombinant Human PTPRN Protein, DDK-tagged | +Inquiry |
PTPRN-4500R | Recombinant Rat PTPRN Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PTPRN-1440HCL | Recombinant Human PTPRN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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