Recombinant Human IGF2, 1-104 aa
Cat.No. : | IGF2-462H |
Product Overview : | Recombinant Human IGF2 (1-104aa) is expressed inE. coli. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IGF2-462H |
Description : | The IGF-II gene encodes a single transcript which results in an 156 amino acid protein, including an 89 amino acid E-domain. ProIGF-II contains sites of O-linked glycosylation. ProIGF-II is converted to mature IGF-II by sequential cleavage after amino acids 104, 87 and 67. Differential glycosylation and cleavage within the E-domain can therefore result in multiple proIGF-II isoforms.The proIGF-II proteins make up 10-20% of circulating IGF-II. ProIGF-II proteins are secreted by some tumor cell lines and levels are elevated in non-islet cell tumor hypoglycemia. |
Source : | Produced recombinantly inE. coli. |
Molecular Weight : | 11949 Da. |
N-terminal Sequence Analysis : | 5 residues > 95 % single sequence. |
Purity : | > 95% by HPLC and N-terminal sequence. |
Biological Activity : | Stimulation of protein synthesis in rat L6 myoblasts. Endotoxin:< 0.1 EU/ug. |
State And Appearance : | Lyophilized white powder.Dried from 0.1M acetic acid under dry nitrogen at a slight vacuum (-25 kPa). |
Detection : | By Western blot Peptide can be biotinylated by ibt upon request. |
Storage/Stability : | At least 2 years at 2 - 4oC (lyophillized). |
Gene Name : | IGF2 insulin-like growth factor 2 (somatomedin A) [ Homo sapiens ] |
Synonyms : | insulin-like growth factor 2 (somatomedin A);INSIGF; pp9974; C11orf43; FLJ22066; FLJ44734; IGF2; insulin-like growth factor 2; IGF-II; somatomedin A; somatomedin-A; insulin-like growth factor II; insulin-like growth factor type 2; putative insulin-like growth factor II associated protein; chromosome 11 open reading frame 43; OTTHUMP00000011157; OTTHUMP00000011018 |
Gene ID : | 3481 |
mRNA Refseq : | NM_000612 |
Protein Refseq : | NP_000603 |
MIM : | 147470 |
UniProt ID : | P01344 |
Chromosome Location : | 11p15.5 |
Pathway : | Diabetes pathways |
Function : | growth factor activity; hormone activity; insulin receptor binding; insulin-like growth factor receptor binding; protein binding |
Products Types
◆ Recombinant Protein | ||
IGF2-4461M | Recombinant Mouse IGF2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGF2-99R | Recombinant Rabbit IGF2 Protein | +Inquiry |
Igf2-44M | Active Recombinant Mouse Igf2 Protein (Ala25-Glu91), N-His tagged, Animal-free, Carrier-free | +Inquiry |
IGF2-2661R | Recombinant Rat IGF2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGF2-1220H | Recombinant Human IGF2 Protein (30-180 aa), GST-tagged | +Inquiry |
◆ Native Protein | ||
IGF2-29116TH | Native Human IGF2 | +Inquiry |
IGF2-621H | Native Human Insulin-Like Growth Factor 2 (somatomedin A) | +Inquiry |
◆ Lysates | ||
IGF2-5266HCL | Recombinant Human IGF2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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