Recombinant Human IL15RA protein, Fc-tagged
Cat.No. : | IL15RA-1655H |
Product Overview : | Recombinant Human IL15RA (Ile31-Thr205) protein was fused to human IgG1 Fc tag at C-terminus and expressed in human 293 cells (HEK293). |
- Specification
- Gene Information
- Related Products
Description : | IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL-15RA, also known as CD215, IL-15 R alpha, is a widely expressed 60 kDa transmembrane glycoprotein. High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. An interleukin (IL)-15 superagonist/IL-15 receptor α fusion complex (IL-15SA/IL-15RA; ALT-803) activates the IL-15 receptor on CD8 T cells and NK cells, and has shown significant anti-tumor. Signal transduction involves SYK. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures. |
Source : | HEK293 |
Species : | Human |
Tag : | human IgG1 Fc |
Predicted N Terminal : | Ile31 |
Form : | Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. |
Molecular Mass : | The protein has a calculated MW of 44.8 kDa. The protein migrates as 60-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Protein length : | Ile31-Thr205 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Storage : | For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IL15RA |
Official Symbol : | IL15RA |
Synonyms : | IL15RA; interleukin 15 receptor, alpha; interleukin-15 receptor subunit alpha; CD215; IL 15RA; MGC104179 |
Gene ID : | 3601 |
mRNA Refseq : | NM_001243539 |
Protein Refseq : | NP_001230468 |
MIM : | 601070 |
UniProt ID : | Q13261 |
Products Types
◆ Recombinant Protein | ||
IL15RA-225H | Recombinant Human IL15RA Protein, hIgG-His-tagged | +Inquiry |
IL15RA-1074H | Recombinant Human IL15RA protein(Ile31-Thr205), His-tagged | +Inquiry |
IL15RA-2292H | Recombinant Human IL15RA Protein, His-tagged | +Inquiry |
Il15ra-1663R | Recombinant Rat Il15ra Protein, His&GST-tagged | +Inquiry |
Il15ra-360M | Active Recombinant Mouse Il15ra Protein, Fc-tagged | +Inquiry |
◆ Lysates | ||
IL15RA-5247HCL | Recombinant Human IL15RA 293 Cell Lysate | +Inquiry |
IL15RA-5246HCL | Recombinant Human IL15RA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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