Recombinant Human IL17RA Protein (Met1-Trp320), C-His tagged

• Cat.No.: IL17RA-4161H
• Product Overview: Recombinant human IL17RA (Met 1-Trp 320) fused with the C-terminal His tag was expressed in Mammalian cells.

Specification

• Description: Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A) . IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F. Ligand and IL 17RA ligation promotes T cell activation and the production of IL - 6, G-CSF, SCF, and multiple pro-inflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5) .
• Source: Mammalian cells
• Species: Human
• Tag: C-His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 35.2 kDa
• Protein Length: Met1-Trp320
• Endotoxin: < 1.0 EU/μg of the protein as determined by the LAL method.
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS or lyophilized from PBS.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: IL17RA interleukin 17 receptor A [ Homo sapiens (human) ]
• Official Symbol: IL17RA
• Synonyms: IL17RA; interleukin 17 receptor A; IL17R, interleukin 17 receptor; interleukin-17 receptor A; CD217; CDw217; hIL 17R; IL 17RA; IL-17 receptor A; IL17R; CANDF5; IL-17RA; hIL-17R; FLJ32274; FLJ36453; MGC10262
• Gene ID: 23765
• mRNA Refseq: NM_014339
• Protein Refseq: NP_055154
• MIM: 605461
• UniProt ID: Q96F46