| Description : |
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Fc |
| Form : |
Lyophilized |
| Molecular Mass : |
62.4 kDa |
| Protein Length : |
541 |
| AA Sequence : |
MNCRELPLTLWVLISVSTAESCTSR PHITVVEGEPFYLKHCSCSLAHEIE TTTKSWYKSSGSQEHVELNPRSSSR IALHDCVLEFWPVELNDTGSYFFQM KNYTQKWKLNVIRRNKHSCFTERQV TSKIVEVKKFFQITCENSYYQTLVN STSLYKNCKKLLLENNKNPTIKKNA EFEDQGYYSCVHFLHHNGKLFNITK TFNITIVEDRSNIVPVLLGPKLNHV AVELGKNVRLNCSALLNEEDVIYWM FGEENGSDPNIHEEKEMRIMTPEGK WHASKVLRIENIGESNLNVLYNCTV ASTGGTDTKSFILVRKADMADIPGH VFTRGMIIAVLILVAVVCLVTVCVI YRVDLVLFYRHLTRRDETLTDGKTY DAFVSYLKECRPENGEEHTFAVEIL PRVLEKHFGYKLCIFERDVVPGGAV VDEIHSLIEKSRRLIIVLSKSYMSN EVRYELESGLHEALVERKIKIILIE FTPVTDFTFLPQSLKLLKSHRVLKW KADKSLSYNSRFWKNLLYLMPAKTV KPGRDEPEVLPVLSES |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
