Description : |
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. |
Species : |
Human |
Form : |
Lyophilized |
Protein Length : |
271 |
AA Sequence : |
MAKVPDMFEDLKNCYSENEEDSSSI DHLSLNQKSFYHVSYGPLHEGCMDQ SVSLSISETSKTSKLTFKESMVVVA TNGKVLKKRRLSLSQSITDDDLEAI ANDSEEEIIKPRSAPFSFLSNVKYN FMRIIKYEFILNDALNQSIIRANDQ YLTAAALHNLDEAVKFDMGAYKSSK DDAKITVILRISKTQLYVTAQDEDQ PVLLKEMPEIPKTITGSETNLLFFW ETHGTKNYFTSVAHPNLFIATKQDY WVCLAGGPPSITDFQILENQA |
Purity : |
> 98% |
Applications : |
WB; ELISA; FACS; FC |
Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
Storage : |
At -20 centigrade. |
Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |