Recombinant Human IL1B Protein
Cat.No. : | IL1B-40H |
Product Overview : | This recombinant protein contains full length of Human interleukin 1β without tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. Similarly, IL-1B has been implicated in human osteoarthritis pathogenesis. Patients with severe Coronavirus Disease 2019 (COVID-19) present elevated levels of pro-inflammatory cytokines such as IL-1B in bronchial alveolar lavage fluid samples. The lung damage induced by the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is to a large extent, a result of the inflammatory response promoted by cytokines such as IL-1B. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. |
Source : | E. coli |
Species : | Human |
Form : | Affinity purified, liquid |
Molecular Mass : | 19.72 kDa |
Purity : | >95% pure by SDS-PAGE |
Applications : | Suitable for use in ELISA, WB and other immune tests |
Storage : | Upon receipt, aliquot and store at ≤ - 20 centigrade. Avoid multiple freeze/thaw cycles |
Storage Buffer : | PBS, pH 7.3 |
Gene Name : | IL1B interleukin 1 beta [ Homo sapiens (human) ] |
Official Symbol : | IL1B |
Synonyms : | IL1B; interleukin 1 beta; IL-1; IL1F2; IL1beta; IL1-BETA; interleukin-1 beta; IL-1 beta; catabolin; interleukin 1beta; preinterleukin 1 beta; pro-interleukin-1-beta |
Gene ID : | 3553 |
mRNA Refseq : | NM_000576 |
Protein Refseq : | NP_000567 |
MIM : | 147720 |
UniProt ID : | P01584 |
Products Types
◆ Recombinant Protein | ||
IL1B-29H | Active Recombinant Human IL1B Protein, Animal Free | +Inquiry |
IL1B-0849H | Recombinant Human IL1B Protein (A117-S269), Tag Free | +Inquiry |
IL1B-364I | Active Recombinant Pig IL1B Protein (154 aa) | +Inquiry |
Il1B-466H | Recombinant Human Il1B, HIgG1 Fc-tagged | +Inquiry |
IL1B-366I | Active Recombinant Human IL1B Protein (153 aa) | +Inquiry |
◆ Lysates | ||
IL1B-853HCL | Recombinant Human IL1B cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket