Recombinant Human IL21, His-tagged
Cat.No. : | IL21-15H |
Product Overview : | Recombinant Human Interleukin-21/IL-21 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln23-Ser155) of Human IL-21 fused with a polyhistidine tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
Source : | Human cells |
Species : | Human |
Tag : | His |
AA Sequence : | QGQDRHMIRMRQLIDIVDQLKNYVN DLVPEFLPAPEDVETNCEWSAFSCF QKAQLKSANTGNNER IINVSIKKLKRKPPSTNAGRRQKHR LTCPSCDSYEKKPPKEFLERFKSLL QKMIHQHLSSRTHGS EDSVDHHHHHH |
Endotoxin : | Less than 0.1 ng/µg (1 IEU/µg). |
Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Storage : | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Gene Name : | IL21 interleukin 21 [ Homo sapiens (human) ] |
Official Symbol : | IL21 |
Synonyms : | IL21; interleukin 21; Za11; IL-21; CVID11; interleukin-21; interleukin-21 isoform |
Gene ID : | 59067 |
mRNA Refseq : | NM_021803 |
Protein Refseq : | NP_068575 |
MIM : | 605384 |
UniProt ID : | Q9HBE4 |
Chromosome Location : | 4q26-q27 |
Pathway : | Cytokine-cytokine receptor interaction; Inflammatory bowel disease (IBD); Jak-STAT signaling pathway |
Function : | cytokine activity; cytokine receptor binding; interleukin-2 receptor binding |
Products Types
◆ Recombinant Protein | ||
IL21-01H | Active Recombinant Human IL21 Protein (aa 32-162), N-Fc-tagged | +Inquiry |
IL21-162M | Active Recombinant Mouse IL21 Protein | +Inquiry |
Il21-3511M | Active Recombinant Mouse Il21 Protein | +Inquiry |
IL21-2694R | Recombinant Rat IL21 Protein, His (Fc)-Avi-tagged | +Inquiry |
Il21-007I | Active Recombinant Rat Il21 Protein (129 aa) | +Inquiry |
◆ Lysates | ||
IL21-001RCL | Recombinant Rat IL21 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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