Recombinant Human IL23A Protein (Arg20-Pro189), His tagged
Cat.No. : | IL23A-3545H |
Product Overview : | Recombinant human IL23A (Arg20-Pro189) protein fused with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | IL-23, which is mainly secreted by antigen-presenting cells, is a member of the IL-12 family, which includes IL-12, IL-27, and IL-35. IL-23 is a heterodimeric cytokine, comprised a unique p19 subunit and p4 subunit, the latter of which is shared with IL-12. The receptor for IL-23 consists of IL-23R and IL-12Rβ1, the latter of which is also characteristic of IL-12. IL-23 is essential for Th17 differentiation, expansion, and survival by binding to its receptor, thereby activating the signaling pathway. Many studies revealed that the IL-23/Th17 pathway is implicated in the pathophysiology of various autoimmune diseases, such as autoimmune arthritis, primary biliary cirrhosis, and inflammatory bowel disease. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 20.17 kDa |
Protein Length : | Arg20-Pro189 |
Purity : | >90 % as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | IL23A interleukin 23, alpha subunit p19 [ Homo sapiens (human) ] |
Official Symbol : | IL23A |
Synonyms : | IL23A; interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; IL 23; IL 23A; IL23P19; interleukin six; G CSF related factor; P19; SGRF; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin 23 p19 subunit; interleukin-23 subunit p19; JKA3 induced upon T-cell activation; interleukin-six, G-CSF related factor; IL-23; IL-23A; MGC79388; |
Gene ID : | 51561 |
mRNA Refseq : | NM_016584 |
Protein Refseq : | NP_057668 |
MIM : | 605580 |
UniProt ID : | Q9NPF7 |
Products Types
◆ Recombinant Protein | ||
Il23A-23H | Recombinant Human Il23A&IL12B Protein, His-tagged | +Inquiry |
Il23a-3516M | Recombinant Mouse Il23a Protein, Myc/DDK-tagged | +Inquiry |
IL23A-4508M | Recombinant Mouse IL23A Protein, His (Fc)-Avi-tagged | +Inquiry |
Il23a-3515M | Active Recombinant Mouse Il23a Protein | +Inquiry |
IL23A-02H | Recombinant Human Active IL23A Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IL23A-5231HCL | Recombinant Human IL23A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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