Recombinant Human IL23A Protein, Fc-tagged
Cat.No. : | IL23A-451H |
Product Overview : | Recombinant Human IL23A (NP_057668.1) (Met1-Pro189) was expressed with the Fc region of human IgG1 at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | IL-23, which is mainly secreted by antigen-presenting cells, is a member of the IL-12 family, which includes IL-12, IL-27, and IL-35[10]. IL-23 is a heterodimeric cytokine, comprised a unique p19 subunit and p40 subunit, the latter of which is shared with IL-12. The receptor for IL-23 consists of IL-23R and IL-12Rβ1, the latter of which is also characteristic of IL-12. IL-23 is essential for Th17 differentiation, expansion, and survival by binding to its receptor, thereby activating the signaling pathway [11,12]. Many studies revealed that the IL-23/Th17 pathway is implicated in the pathophysiology of various autoimmune diseases, such as autoimmune arthritis[13], primary biliary cirrhosis[14], and inflammatory bowel disease[15]. |
Source : | HEK293 |
Species : | Human |
Tag : | Fc |
Predicted N Terminal : | Arg 20 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 %- 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant human IL23A consists of 408 amino acids and predicts a molecular mass of 45.4 kDa. |
Protein length : | Met1-Pro189 |
Endotoxin : | < 1.0 EU per μg protein as determined by the LAL method. |
Purity : | > 85 % as determined by SDS-PAGE. |
Storage : | Samples are stable for up to twelve months from date of receipt at-70 centigrade. Store it under sterile conditions at-20 centigrade to-80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | IL23A interleukin 23, alpha subunit p19 [ Homo sapiens ] |
Official Symbol : | IL23A |
Synonyms : | IL23A; interleukin 23, alpha subunit p19; interleukin-23 subunit alpha; IL 23; IL 23A; IL23P19; interleukin six; G CSF related factor; P19; SGRF; IL-23-A; IL-23p19; IL-23 subunit alpha; interleukin 23 p19 subunit; interleukin-23 subunit p19; JKA3 induced upon T-cell activation; interleukin-six, G-CSF related factor; IL-23; IL-23A; MGC79388; |
Gene ID : | 51561 |
mRNA Refseq : | NM_016584 |
Protein Refseq : | NP_057668 |
MIM : | 605580 |
UniProt ID : | Q9NPF7 |
Products Types
◆ Recombinant Protein | ||
IL23A-4508M | Recombinant Mouse IL23A Protein, His (Fc)-Avi-tagged | +Inquiry |
IL23A-364C | Recombinant Cynomolgus Monkey IL23A Protein, His (Fc)-Avi-tagged | +Inquiry |
IL23A-2067R | Recombinant Rhesus Macaque IL23A Protein, His (Fc)-Avi-tagged | +Inquiry |
IL23A-01H | Active Recombinant Human IL23A Protein, Myc/DDK-tagged | +Inquiry |
Il23a-3515M | Active Recombinant Mouse Il23a Protein | +Inquiry |
◆ Lysates | ||
IL23A-5231HCL | Recombinant Human IL23A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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