Recombinant Human IL27RA protein, His & T7-tagged

• Cat.No.: IL27RA-5788H
• Product Overview: Recombinant Human IL27RA aa. (Glu123~Pro343 (Accession # Q6UWB1)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. This gene encodes a protein which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.
• Source: E. coli
• Species: Human
• Tag: His & T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 28.2kDa
• Protein length: Glu123~Pro343 (Accession # Q6UWB1)
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 5.4.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: IL27RA interleukin 27 receptor subunit alpha [ Homo sapiens (human) ]
• Official Symbol: IL27RA
• Synonyms: CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; T-cell cytokine receptor type 1; class I cytokine receptor; cytokine receptor WSX-1; cytokine receptor-like 1; interleukin 27 receptor, alpha; type I T-cell cytokine receptor; interleukin-27 receptor subunit alpha
• Gene ID: 9466
• mRNA Refseq: NM_004843.3
• Protein Refseq: NP_004834.1
• UniProt ID: Q6UWB1