Recombinant Human IL34 protein, His-tagged

• Cat.No.: IL34-2141H
• Product Overview: Recombinant Human IL34 protein(Q6ZMJ4-1)(Asn 21 - Pro 242), fused with C-terminal His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: C-His
• Protein length: Asn 21 - Pro 242
• Form: Lyophilized from 0.22 μm filtered solution in PBS, 0.2 M Arginine, pH7.4 with trehalose as protectant.
• Bio-activity: Immobilized Human M-CSF R, Mouse IgG2a Fc Tag (MALS verified) at 5 μg/mL (100 μL/well) can bind Human IL-34, His Tag with a linear range of 0.4-2 ng/mL.
• Molecular Mass: The protein has a calculated MW of 27.3 kDa. The protein migrates as 32 kDa and 35-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >90% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  Please avoid repeated freeze-thaw cycles.
  This product is stable after storage at:
  -20°C to -70°C for 12 months in lyophilized state;
  -70°C for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: IL34 interleukin 34 [ Homo sapiens ]
• Official Symbol: IL34
• Synonyms: IL34; interleukin 34; C16orf77, chromosome 16 open reading frame 77; interleukin-34; IL 34; MGC34647; IL-34; C16orf77
• Gene ID: 146433
• mRNA Refseq: NM_001172771
• Protein Refseq: NP_001166242
• MIM: 612081
• UniProt ID: Q6ZMJ4

Reviews

05/10/2021

IL34 has shown good biocompatibility and safety in related experiments.

01/19/2020

When using IL34 for experiments, the experimental conditions and results are highly repeatable.

10/24/2019

Quality is stable and reliable, with no significant differences between batches.

Q&As

What is the effect of IL34 on tumor prognosis?

There are no clear studies showing the effect of IL34 on tumor prognosis.

What are the advantages of IL34 over other treatments?

Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.

What is the mechanism of action of IL34 in the treatment of tumor?

May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.

How is the clinical trial of IL34 progressing?

No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.

How does IL34 affect the immune system?

Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.

How to evaluate the efficacy of IL34?

The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.