Recombinant Human IL6R, Fc-tagged
Cat.No. : | IL6R-322H |
Product Overview : | The extracellular domain of human IL-6R (aa 20-359) is fused to the N-terminus of the Fc region of human IgG1. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-6 (IL-6) is a multifunctional factor, which exerts its activities through binding to a highaffinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low affinity (IL-6Ralpha;) and a signal transducing component of 130 kDa (gp130) that does not bind IL-6 by itself, but is required for highaffinity binding of IL-6 by the complex. A soluble form of the IL-6Rα has been found in the urine of healthy adult humans. |
Source : | CHO Cells |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
Purity : | ≥98% (SDS-PAGE) |
Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. Avoid freeze/thaw cycles. |
Gene Name : | IL6R interleukin 6 receptor [ Homo sapiens ] |
Official Symbol : | IL6R |
Synonyms : | IL6R; interleukin 6 receptor; interleukin-6 receptor subunit alpha; CD126; IL-6R 1; CD126 antigen; membrane glycoprotein 80; IL-6 receptor subunit alpha; gp80; IL6RA; IL-6RA; IL-6R-1; MGC104991; |
Gene ID : | 3570 |
mRNA Refseq : | NM_000565 |
Protein Refseq : | NP_000556 |
MIM : | 147880 |
UniProt ID : | P08887 |
Chromosome Location : | 1q21 |
Pathway : | Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; IL-6 Signaling Pathway, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem; |
Function : | ciliary neurotrophic factor binding; contributes_to ciliary neurotrophic factor receptor activity; enzyme binding; interleukin-6 binding; contributes_to interleukin-6 receptor activity; contributes_to interleukin-6 receptor binding; protein binding; protein homodimerization activity; receptor activity; |
Products Types
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IL6R-2176H | Recombinant Human IL6R Protein, MYC/DDK-tagged | +Inquiry |
IL6R-584H | Active Recombinant Human IL6R Protein | +Inquiry |
◆ Lysates | ||
IL6R-2903HCL | Recombinant Human IL6R cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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