Recombinant Human Interleukin 10, His-tagged
Cat.No. : | IL10-530H |
Product Overview : | Recombinant IL10 protein, fused to His-tag at N-terminus, was expressed in E. coli and was purified by conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL10-530H |
Description : | Interleukin-10 (IL 10) is also known as human cytokine synthesis inhibitory factor (CSIF) and inhibits the synthesis of pro-inflammatory cytokines like IFN-gamma, IL2, IL3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. This protein has effects in immunoregulation and inflammation and down-regulates the expression of Th1 cytokines, MHC class II proteins, and costimulatory molecules on macrophages. |
Concentration : | 0.5 mg/ml |
Source : | Human |
Host : | E.coli |
Form : | Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 20% glycerol. |
Purity : | > 95% by SDS - PAGE |
Sequence : | 19-178 amino acids: MGSSHHHHHH SSGLVPRGSH MSPGQGTQSE NSCTHFPGNL PNMLRDLRDA FSRVKTFFQM KDQLDNLLLK ESLLEDFKGY LGCQALSEMI QFYLEEVMPQ AENQDPDIKA HVNSLGENLK TLRLRLRRCH RFLPCENKSK AVEQVKNAFN KLQEKGIYKA MSEFDIFINY IEAYMTMKIR N |
Molecular Mass : | 20.94 kDa (181 aa), confirmed by MALDI-TOF. |
Applications : | SDS-PAGE |
Endotoxin Levels : | < 1.0 EU per ug of protein (determined by LAL method) |
Storage : | Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Gene Name : | IL10 interleukin 10 [ Homo sapiens ] |
Official Symbol : | IL10 |
Synonyms : | CSIF; IL10A; MGC1264 50; MGC126451; TGIF; B-TCGF; IL-10; Cytokine synthesis inhibitory factor; Interleukin-10 precursor; IL10; interleukin 10 |
Gene ID : | 3586 |
mRNA Refseq : | NM_000572 |
Protein Refseq : | NP_000563 |
MIM : | 124092 |
UniProt ID : | P22301 |
Chromosome Location : | 1q31-q32 |
Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; T cell receptor signaling pathway |
Function : | cytokine activity; interleukin-10 receptor binding; protein binding |
Products Types
◆ Recombinant Protein | ||
IL10-4400M | Recombinant Monkey IL10 Protein | +Inquiry |
IL10-060H | Active Recombinant Human IL10 Protein | +Inquiry |
il10-998Z | Recombinant Zebrafish il10 Protein, His-tagged | +Inquiry |
IL10-0021H | Recombinant Human IL10 Protein | +Inquiry |
Il10-084M | Recombinant Mouse Il10 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
IL10-2079HCL | Recombinant Human IL10 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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