Recombinant Human ITM2C Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ITM2C-2959H |
Product Overview : | ITM2C MS Standard C13 and N15-labeled recombinant protein (NP_001012532) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 25 kDa |
AA Sequence : | MVKISFQPAVAGIKGDKADKASASA PAPASATEILLTPARLARDNFFRCG VLYEDSLSSQVRTQMELEEDVKIYL DENYERINVPVPQFGGGDPADIIHD FQRGLTAYHDISLDKCYVIELNTTI VLPPRNFWELLMNVKRGTYLPQTYI IQEEMVVTEHVSDKEALGSFIYHLC NGKDTYRLRRRATRRRINKRGAKNC NAIRHFENTFVVETLICGVVTRTRP LEQKLISEEDLAANDILDYKDDDDK V |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ITM2C integral membrane protein 2C [ Homo sapiens (human) ] |
Official Symbol : | ITM2C |
Synonyms : | ITM2C; integral membrane protein 2C; BRI3; E25; hRPC.1050_D_4; ITM3; E25C; HRPC.1050_D_4; |
Gene ID : | 81618 |
mRNA Refseq : | NM_001012514 |
Protein Refseq : | NP_001012532 |
MIM : | 609554 |
UniProt ID : | Q9NQX7 |
Products Types
◆ Recombinant Protein | ||
Itm2c-3617M | Recombinant Mouse Itm2c Protein, Myc/DDK-tagged | +Inquiry |
ITM2C-379C | Recombinant Cynomolgus Monkey ITM2C Protein, His (Fc)-Avi-tagged | +Inquiry |
ITM2C-4651M | Recombinant Mouse ITM2C Protein, His (Fc)-Avi-tagged | +Inquiry |
ITM2C-2777R | Recombinant Rat ITM2C Protein, His (Fc)-Avi-tagged | +Inquiry |
ITM2C-8383M | Recombinant Mouse ITM2C Protein | +Inquiry |
◆ Lysates | ||
ITM2C-5116HCL | Recombinant Human ITM2C 293 Cell Lysate | +Inquiry |
ITM2C-5114HCL | Recombinant Human ITM2C 293 Cell Lysate | +Inquiry |
ITM2C-5115HCL | Recombinant Human ITM2C 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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