Recombinant Human KLRC1 Protein
Cat.No. : | KLRC1-4917H |
Product Overview : | Human KLRC1 full-length ORF (NP_002250.1) recombinant protein without tag. |
- Specification
- Gene Information
- Related Products
Description : | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Form : | Liquid |
Molecular Mass : | 26.3 kDa |
AA Sequence : | MDNQGVIYSDLNLPPNPKRQQRKPK GNKSSILATEQEITYAELNLQKASQ DFQGNDKTYHCKDLPSAPEKLIVGI LGIICLILMASVVTIVVIPSTLIQR HNNSSLNTRTQKARHCGHCPEEWIT YSNSCYYIGKERRTWEESLLACTSK NSSLLSIDNEEEMKFLSIISPSSWI GVFRNSSHHPWVTMNGLAFKHEIKD SDNAELNCAVLQVNRLKSAQCGSSI IYHCKHKL |
Applications : | Antibody Production Functional Study Compound Screening |
Usage : | Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
Gene Name : | KLRC1 killer cell lectin-like receptor subfamily C, member 1 [ Homo sapiens ] |
Official Symbol : | KLRC1 |
Synonyms : | KLRC1; killer cell lectin-like receptor subfamily C, member 1; NKG2; NKG2-A/NKG2-B type II integral membrane protein; CD159a; NKG2 1/B activating NK receptor; NKG2 A; NKG2 B; NK cell receptor A; C-lectin type II protein; natural killer cell lectin; natural killer group protein 2; NKG2-1/B activating NK receptor; NKG2-A/B-activating NK receptor; CD159 antigen-like family member A; NKG2-A/B type II integral membrane protein; NKG2A; CD159A; MGC13374; MGC59791; |
Gene ID : | 3821 |
mRNA Refseq : | NM_002259 |
Protein Refseq : | NP_002250 |
MIM : | 161555 |
UniProt ID : | P26715 |
Products Types
◆ Lysates | ||
KLRC1-986CCL | Recombinant Cynomolgus KLRC1 cell lysate | +Inquiry |
KLRC1-924MCL | Recombinant Mouse KLRC1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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