Recombinant Human KLRC1 Protein, C-His-tagged
Cat.No. : | KLRC1-088H |
Product Overview : | Recombinant Human KLRC1 Protein with C-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The KIR/LIR family includes p91A (also designated pp130 or PIR-B, for paired immunoglobulin-like receptor-B) and p91B (also designated PIR-A). p91A acts as an inhibitory receptor through interactions with SHP-1, whereas p91B acts as an activating receptor. CD94, NKG2 and Ly-49 are members of the C-type lectin superfamily of type II membrane glycoproteins. CD94 forms heterodimers with NKG2 isoforms on the surface of NK cells, whereas Ly-49 isoforms form homodimers. NKG2-D, expressed on NK cells, gdT cells and CD8+αβ T cells, is a receptor for the stress inducible protein MICA, an antigen frequently expressed in epithelial tumors. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Molecular Mass : | ~15 kDa |
AA Sequence : | PSTLIQRHNNSSLNTRTQKARHCGH CPEEWITYSNSCYYIGKERRTWEES LLACTSKNSSLLSIDNEEEMKFLSI ISPSSWIGVFRNSSHHPWVTMNGLA FKHEIKDSDNAELNCAVLQVNRLKS AQCGSSIIYHCKHKL |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Concentration : | ≥0.5 mg/mL |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | KLRC1 killer cell lectin-like receptor subfamily C, member 1 [ Homo sapiens (human) ] |
Official Symbol : | KLRC1 |
Synonyms : | KLRC1; killer cell lectin-like receptor subfamily C, member 1; NKG2; NKG2-A/NKG2-B type II integral membrane protein; CD159a; NKG2 1/B activating NK receptor; NKG2 A; NKG2 B; NK cell receptor A; C-lectin type II protein; natural killer cell lectin; natural killer group protein 2; NKG2-1/B activating NK receptor; NKG2-A/B-activating NK receptor; CD159 antigen-like family member A; NKG2-A/B type II integral membrane protein; NKG2A; CD159A; MGC13374; MGC59791; |
Gene ID : | 3821 |
mRNA Refseq : | NM_002259 |
Protein Refseq : | NP_002250 |
MIM : | 161555 |
UniProt ID : | P26715 |
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◆ Lysates | ||
KLRC1-986CCL | Recombinant Cynomolgus KLRC1 cell lysate | +Inquiry |
KLRC1-924MCL | Recombinant Mouse KLRC1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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