Recombinant Human KLRC3 Protein, GST-tagged
Cat.No. : | KLRC3-4913H |
Product Overview : | Human KLRC3 partial ORF ( NP_002252, 132 a.a. - 240 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 37.73 kDa |
AA Sequence : | GKERRTWEESLQACASKNSSSLLSI DNEEEMKFLASILPSSWIGVFRNSS HHPWVTINGLAFKHEIKDSDHAERN CAMLHVRGLISDQCGSSRIIRRGFI MLTRLVLNS |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | KLRC3 killer cell lectin-like receptor subfamily C, member 3 [ Homo sapiens ] |
Official Symbol : | KLRC3 |
Synonyms : | KLRC3; killer cell lectin-like receptor subfamily C, member 3; NKG2-E type II integral membrane protein; NKG2 E; NK cell receptor E; NKG2-E-activating NK receptor; NKG2E; NKG2-E; |
Gene ID : | 3823 |
mRNA Refseq : | NM_002261 |
Protein Refseq : | NP_002252 |
MIM : | 602892 |
UniProt ID : | Q07444 |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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