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Recombinant Human KRT8 Protein (Gln90-Gln236), His tagged

Cat.No. : KRT8-2112H
Product Overview : Recombinant human CK-8 (Gln90-Gln236) fused with His tag was expressed in E. coli.
  • Specification
  • Gene Information
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Description : Keratin8 (KRT8) is the major component of the intermediate filament cytoskeleton and predominantly expressed in simple epithelial tissues. Aberrant expression of KRT8 is associated with multiple tumor progression and metastasis. KRT8 overexpression in renal cancer cell lines promoted cell migration and invasion. In contrast, KRT8 knockdown suppressed ccRCC metastasis both in vitro and in vivo. KRT8 expression may therefore be a biomarker or potential therapeutic target to identify patients with worse survival.
Source : E. coli
Species : Human
Tag : His
Form : Lyophilized powder/frozen liquid
Molecular Mass : 19.15 kDa
Protein Length : Gln90-Gln236
Purity : >90% as determined by SDS-PAGE
Notes : For research use only.
Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
Storage Buffer : Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
Reconstitution : Reconstitute in sterile water for a stock solution.
Shipping : They are shipped out with dry ice/blue ice unless customers require otherwise.
Gene Name : KRT8 keratin 8 [ Homo sapiens (human) ]
Official Symbol : KRT8
Synonyms : KRT8; keratin 8; K8; KO; CK8; CK-8; CYK8; K2C8; CARD2; keratin, type II cytoskeletal 8; cytokeratin-8; keratin 8, type II; type-II keratin Kb8
Gene ID : 3856
mRNA Refseq : NM_002273
Protein Refseq : NP_002264
MIM : 148060
UniProt ID : P05787

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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