Recombinant Human LRRC8A Protein, MYC/DDK-tagged

• Cat.No.: LRRC8A-970H
• Product Overview: Recombinant human LRRC8A protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008].
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 94 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: leucine rich repeat containing 8 VRAC subunit A [ Homo sapiens ]
• Official Symbol: LRRC8A
• Synonyms: AGM5; LRRC8; SWELL1
• Gene ID: 56262
• mRNA Refseq: NM_001127244.1
• Protein Refseq: NP_001120716.1
• MIM: 608360
• UniProt ID: A8K1C7