Recombinant Human lysyl oxidase, His-tagged
Cat.No. : | LOX-608H |
Product Overview : | LOX, 169-417aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. Recombinant human LOX protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol |
Molecular Mass : | 31.4 kDa (272aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSDDPYNPY KYSDDNPYYN YYDTYERPRP GGRYRPGYGT GYFQYGLPDL VADPYYIQAS TYVQKMSMYN LRCAAEENCL ASTAYRADVR DYDHRVLLRF PQRVKNQGTS DFLPSRPRYS WEWHSCHQHY HSMDEFSHYD LLDANTQRRV AEGHKASFCL EDTSCDYGYH RRFACTAHTQ GLSPGCYDTY GADIDCQWID ITDVKPGNYI LKVSVNPSYL VPESDYTNNV VRCDIRYTGH HAYASGCTIS PY |
Purity : | >85% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | LOX lysyl oxidase [ Homo sapiens ] |
Official Symbol : | LOX |
Synonyms : | LOX; lysyl oxidase; protein-lysine 6-oxidase; MGC105112; |
Gene ID : | 4015 |
mRNA Refseq : | NM_001178102 |
Protein Refseq : | NP_001171573 |
MIM : | 153455 |
UniProt ID : | P28300 |
Chromosome Location : | 5q23.3-q31.2 |
Function : | copper ion binding; metal ion binding; oxidoreductase activity; protein-lysine 6-oxidase activity; |
Products Types
◆ Recombinant Protein | ||
LOX-91H | Active Recombinant Human LOX Protein, Myc/DDK-tagged | +Inquiry |
lox-1564P | Recombinant Pseudomonas aeruginosa lox Protein (M1-I678) | +Inquiry |
LOX-4734H | Recombinant Human LOX Protein, GST-tagged | +Inquiry |
LOX-5130M | Recombinant Mouse LOX Protein, His (Fc)-Avi-tagged | +Inquiry |
LOX-1310H | Recombinant Human LOX Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
LOX-41 | Active Native Lactate Oxidase | +Inquiry |
◆ Lysates | ||
LOX-4677HCL | Recombinant Human LOX 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1061 | Lipoxygenase Activity Assay Kit (Fluorometric) | +Inquiry |
Kit-2318 | 5-Lipoxygenase Inhibitor Screening Kit (Fluorometric) | +Inquiry |
Kit-0520 | LOX Fluorometric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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