Recombinant Human MECP2 Protein, GST-tagged
Cat.No. : | MECP2-4484H |
Product Overview : | Human MECP2 full-length ORF ( NP_004983.1, 1 a.a. - 486 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 78.8 kDa |
AA Sequence : | MVAGMLGLREEKSEDQDLQGLKDKP LKFKKVKKDKKEEKEGKHEPVQPSA HHSAEPAEAGKAETSEGSGSAPAVP EASASPKQRRSIIRDRGPMYDDPTL PEGWTRKLKQRKSGRSAGKYDVYLI NPQGKAFRSKVELIAYFEKVGDTSL DPNDFDFTVTGRGSPSRREQKPPKK PKSPKAPGTGRGRGRPKGSGTTRPK AATSEGVQVKRVLEKSPGKLLVKMP FQTSPGGKAEGGGATTSTQVMVIKR PGRKRKAEADPQAIPKKRGRKPGSV VAAAAAEAKKKAVKESSIRSVQETV LPIKKRKTRETVSIEVKEVVKPLLV STLGEKSGKGLKTCKSPGRKSKESS PKGRSSSASSPPKKEHHHHHHHSES PKAPVPLLPPLPPPPPEPESSEDPT SPPEPQDLSSSVCKEEKMPRGGSLE SDGCPKEPAKTQPAVATAATAAEKY KHRGEGERKDIVSSSMPRPNREEPV DSRTPVTERVS |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | MECP2 methyl CpG binding protein 2 (Rett syndrome) [ Homo sapiens ] |
Official Symbol : | MECP2 |
Synonyms : | MECP2; methyl CpG binding protein 2 (Rett syndrome); mental retardation, X linked 16 , mental retardation, X linked 79 , MRX16, MRX79, RTT; methyl-CpG-binding protein 2; meCp-2 protein; RS; RTS; RTT; PPMX; MRX16; MRX79; MRXSL; AUTSX3; MRXS13; DKFZp686A24160; |
Gene ID : | 4204 |
mRNA Refseq : | NM_001110792 |
Protein Refseq : | NP_001104262 |
MIM : | 300005 |
UniProt ID : | P51608 |
Products Types
◆ Recombinant Protein | ||
MECP2-1549H | Recombinant Human MECP2 Protein, His-tagged | +Inquiry |
MECP2-428C | Recombinant Cynomolgus Monkey MECP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MECP2-2534R | Recombinant Rhesus Macaque MECP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MECP2-3289R | Recombinant Rat MECP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MECP2-334H | Recombinant Human MECP2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
MECP2-4395HCL | Recombinant Human MECP2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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