Recombinant Human MECP2 Protein, His-tagged
Cat.No. : | MECP2-334H |
Product Overview : | Active Full length Recombinant Human MECP2 (Methyl CpG Binding Protein 2) Protein is produced in SF9 Insect Cells and is fused with a His tag at the N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | MeCP2 (UniProt/Swiss-Prot entry P51608) is a chromosomal protein with abundant binding sites in the chromatin. It belongs to the family of methyl CpG binding proteins which also comprises MBD1, MBD2, MBD3 and MBD4. MeCP2 can bind specifically to methylated promoters, thereby repressing transcription. This transcriptional repression is mediated through interaction with histone deacetylase and the corepressor SIN3A. MeCP2 also is essential for development. Mutations in MeCP2 are the cause of several types of mental retardation including Rett syndrome, a progressive neurological disorder that causes mental retardation in females and mental retardation syndromic X-linked type 13, and may also be involved in Angelman syndrome and susceptibility to some types of autism. |
Source : | Insect Cells |
Species : | Human |
Tag : | His |
Form : | 20mM Tris-Cl pH 7.6, 1 mM EDTA, 0.15 M NaCl, 10% glycerol, 0.5 mM PMSF and 1 mM DTT. |
Purity : | Purified using FPLC, >95% purity as determined by SDS-PAGE. |
Notes : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Stability : | Guaranteed stable for 2 years from date of receipt when stored properly. |
Storage : | Store at -80 centigrade. |
Concentration : | 0.5 µg/µl |
Gene Name : | MECP2 methyl CpG binding protein 2 (Rett syndrome) [ Homo sapiens ] |
Official Symbol : | MECP2 |
Synonyms : | MECP2; methyl CpG binding protein 2 (Rett syndrome); meCp-2 protein; RS; RTS; RTT; PPMX; MRX16; MRX79; MRXSL; AUTSX3; MRXS13; DKFZp686A24160; |
Gene ID : | 4204 |
mRNA Refseq : | NM_001110792 |
Protein Refseq : | NP_001104262 |
MIM : | 300005 |
UniProt ID : | P51608 |
Products Types
◆ Recombinant Protein | ||
MECP2-2534R | Recombinant Rhesus Macaque MECP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MECP2-1549H | Recombinant Human MECP2 Protein, His-tagged | +Inquiry |
MECP2-3289R | Recombinant Rat MECP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MECP2-428C | Recombinant Cynomolgus Monkey MECP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MECP2-4484H | Recombinant Human MECP2 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
MECP2-4395HCL | Recombinant Human MECP2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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