Recombinant Human MLH1 protein, His-tagged
Cat.No. : | MLH1-1290H |
Product Overview : | Recombinant Human MLH1 protein(Met1~Thr347), fused with N-terminal His Tag, was expressed in E.coli. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300. |
Molecular Mass : | 44kDa |
Protein Length : | Met1~Thr347 |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | > 97% |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Reconstitution : | Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name : | MLH1 mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) [ Homo sapiens ] |
Official Symbol : | MLH1 |
Synonyms : | MLH1; mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli); COCA2, mutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2); DNA mismatch repair protein Mlh1; FCC2; HNPCC; HNPCC2; COCA2; hMLH1; MGC5172; |
Gene ID : | 4292 |
mRNA Refseq : | NM_000249 |
Protein Refseq : | NP_000240 |
MIM : | 120436 |
UniProt ID : | P40692 |
Products Types
◆ Recombinant Protein | ||
MLH1-5385H | Recombinant Human MLH1 Protein, GST-tagged | +Inquiry |
MLH1-5580M | Recombinant Mouse MLH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Mlh1-4089M | Recombinant Mouse Mlh1 Protein, Myc/DDK-tagged | +Inquiry |
MLH1-3357R | Recombinant Rat MLH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MLH1-233H | Recombinant Human MLH1, StrepII-tagged | +Inquiry |
◆ Lysates | ||
MLH1-4295HCL | Recombinant Human MLH1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGermline mutations in MLH1 are linked to Lynch syndrome, increasing the risk of various cancers.
MLH1 helps prevent the development of colorectal and other hereditary cancers by maintaining DNA integrity.
Changes in MLH1 function can influence the effectiveness of certain chemotherapies in treating cancer.
MLH1 plays a role in the cellular response to DNA damage, maintaining replication accuracy.
MLH1 deficiency results in microsatellite instability, a hallmark of certain types of cancer.
MLH1 is essential for DNA mismatch repair, ensuring genomic stability by correcting replication errors.
MLH1 modulates apoptosis in cells with DNA damage, preventing the proliferation of damaged cells.
Customer Reviews (3)
Write a reviewTimely protein expression optimization, greatly boosts our research.
Accurate protein structural analysis, a cornerstone of our investigations.
Precise antibody validation, enhances our immunoprecipitation accuracy.
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