| Description : |
Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
224.2 kDa |
| AA Sequence : |
MTDAQMADFGAAAQYLRKSEKERLE AQTRPFDIRTECFVPDDKEEFVKAK ILSREGGKVIAETENGKTVTVKEDQ VLQQNPPKFDKIEDMAMLTFLHEPA VLFNLKERYAAWMIYTYSGLFCVTV NPYKWLPVYNAEVVAAYRGKKRSEA PPHIFSISDNAYQYMLTDRENQSIL ITGESGAGKTVNTKRVIQYFASIAA IGDRGKKDNANANKGTLEDQIIQAN PALEAFGNAKTVRNDNSSRFGKFIR IHFGATGKLASADIETYLLEKSRVI FQLKAERNYHIFYQILSNKKPELLD MLLVTNNPYDYAFVSQGEVSVASID DSEELMATDSAFDVLGFTSEEKAGV YKLTGAIMHYGNMKFKQKQREEQAE PDGTEDADKSAYLMGLNSADLLKGL CHPRVKVGNEYVTKGQSVQQVYYSI GALAKAVYEKMFNWMVTRINATLET KQPRQYFIGVLDIAGFEIFDFNSFE QLCINFTNEKLQQFFNHHMFVLEQE EYKKEGIEWTFIDFGMDLQACIDLI EKPMGIMSILEEECMFPKATDMTFK AKLYDNHLGKSNNFQKPRNIKGKQE AHFSLIHYAGTVDYNILGWLEKNKD PLNETVVALYQKSSLKLMATLFSSY ATADTGDSGKSKGGKKKGSSFQTVS ALHRENLNKLMTNLRTTHPHFVRCI IPNERKAPGVMDNPLVMHQLRCNGV LEGIRICRKGFPNRILYGDFRQRYR ILNPVAIPEGQFIDSRKGTEKLLSS LDIDHNQYKFGHTKVFFKAGLLGLL EEMRDERLSRIITRMQAQARGQLMR IEFKKIVERRDALLVIQWNIRAFMG VKNWPWMKLYFKIKPLLKSAETEKE MATMKEEFGRIKETLEKSEARRKEL EEKMVSLLQEKNDLQLQVQAEQDNL NDAEERCDQLIKNKIQLEAKVKEMN ERLEDEEEMNAELTAKKRKLEDECS ELKKDIDDLELTLAKVEKEKHATEN KVKNLTEEMAGLDEIIAKLTKEKKA LQEAHQQALDDLQVEEDKVNSLSKS KVKLEQQVDDLEGSLEQEKKVRMDL ERAKRKLEGDLKLTQESIMDLENDK LQLEEKLKKKEFDINQQNSKIEDEQ VLALQLQKKLKENQARIEELEEELE AERTARAKVEKLRSDLSRELEEISE RLEEAGGATSVQIEMNKKREAEFQK MRRDLEEATLQHEATAAALRKKHAD SVAELGEQIDNLQRVKQKLEKEKSE FKLELDDVTSNMEQIIKAKANLEKV SRTLEDQANEYRVKLEEAQRSLNDF TTQRAKLQTENGELARQLEEKEALI SQLTRGKLSYTQQMEDLKRQLEEEG KAKNALAHALQSARHDCDLLREQYE EETEAKAELQRVLSKANSEVAQWRT KYETDAIQRTEELEEAKKKLAQRLQ DAEEAVEAVNAKCSSLEKTKHRLQN EIEDLMVDVERSNAAAAALDKKQRN FDKILAEWKQKYEESQSELESSQKE ARSLSTELFKLKNAYEESLEHLETF KRENKNLQEEISDLTEQLGEGGKNV HELEKVRKQLEVEKLELQSALEEAE ASLEHEEGKILRAQLEFNQIKAEIE RKLAEKDEEMEQAKRNHQRVVDSLQ TSLDAETRSRNEVLRVKKKMEGDLN EMEIQLSHANRMAAEAQKQVKSLQS LLKDTQIQLDDAVRANDDLKENIAI VERRNNLLQAELEELRAVVEQTERS RKLAEQELIETSERVQLLHSQNTSL INQKKKMESDLTQLQSEVEEAVQEC RNAEEKAKKAITDAAMMAEELKKEQ DTSAHLERMKKNMEQTIKDLQHRLD EAEQIALKGGKKQLQKLEARVRELE GELEAEQKRNAESVKGMRKSERRIK ELTYQTEEDKKNLLRLQDLVDKLQL KVKAYKRQAEEAEEQANTNLSKFRK VQHELDEAEERADIAESQVNKLRAK SRDIGAKQKMHDEETRTRPLEQKLI SEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
