Recombinant Human NEUROD1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NEUROD1-3217H
• Product Overview: NEUROD1 MS Standard C13 and N15-labeled recombinant protein (NP_002491) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 39.9 kDa
• AA Sequence: MTKSYSESGLMGEPQPQGPPSWTDE CLSSQDEEHEADKKEDDLEAMNAEE DSLRNGGEEEDEDEDLEEEEEEEEE DDDQKPKRRGPKKKKMTKARLERFK LRRMKANARERNRMHGLNAALDNLR KVVPCYSKTQKLSKIETLRLAKNYI WALSEILRSGKSPDLVSFVQTLCKG LSQPTTNLVAGCLQLNPRTFLPEQN QDMPPHLPTASASFPVHPYSYQSPG LPSPPYGTMDSSHVFHVKPPPHAYS AALEPFFESPLTDCTSPSFDGPLSP PLSINGNFSFKHEPSAEFEKNYAFT MHYPAATLAGAQSHGSIFSGTAAPR CEIPIDNIMSFDSHSHHERVMSAQL NAIFHDTRTRPLEQKLISEEDLAAN DILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NEUROD1 neuronal differentiation 1 [ Homo sapiens (human) ]
• Official Symbol: NEUROD1
• Synonyms: NEUROD1; neuronal differentiation 1; NEUROD, neurogenic differentiation 1; neurogenic differentiation factor 1; beta cell E box transactivator 2; BETA2; BHF 1; bHLHa3; MODY6; NeuroD; neurogenic helix loop helix protein NEUROD; beta-cell E-box transactivator 2; class A basic helix-loop-helix protein 3; neurogenic helix-loop-helix protein NEUROD; basic helix-loop-helix transcription factor; BHF-1; NEUROD
• Gene ID: 4760
• mRNA Refseq: NM_002500
• Protein Refseq: NP_002491
• MIM: 601724
• UniProt ID: Q13562